DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art4 and Mettl27

DIOPT Version :9

Sequence 1:	NP_001262445.1	Gene:	Art4 / 41219	FlyBaseID:	FBgn0037770	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	XP_006504585.1	Gene:	Mettl27 / 79565	MGIID:	1933146	Length:	266	Species:	Mus musculus

Alignment Length:	197	Identity:	39/197 - (19%)
Similarity:	75/197 - (38%)	Gaps:	46/197 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 RAILGNAVDFQDKIVLDVGAGSGILSFFAVQAGAAKVYAIEAS-NMAQYAQQLVESNNVQHKIS- 231
            ||..|:.   .|.::|||..|:|:::......|..:|..::.| .|.:.|:    :..:.|.:|
Mouse    60 RAFRGSP---HDALILDVACGTGLVAVELQARGFLQVQGVDGSPEMLKQAR----ARGLYHHLSL 117

  Fly   232 ------------------VIPGKIEEIE-----LPEKVDVIISEPMGYMLYNERMLETYLHARKW 273
                              :|.|.:.|.:     :||.:.|  ::| |...:...:...|.|.|:.
Mouse   118 CTLGQEPLPDPEGTFDAVIIVGALSEGQVPCSAIPELLRV--TKP-GSCPHQTTVTVGYSHDREA 179

  Fly   274 LKPQGKMYPTHGDLHIAPFSDESLYSEQYNKANFWYQSAFHGVDLTTLHKEGMKEYFRQPIVDTF 338
            .  ...:.|..|.|        ...:.:.|.:|..|:...... |.:|.:.|:.|......||.:
Mouse   180 F--ASALVPDRGGL--------VCLTTRTNPSNLPYKETLEAT-LDSLERAGVWECLVTQPVDHW 233

  Fly   339 DI 340
            ::
Mouse   234 EL 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art4	NP_001262445.1	PH-like	24..134	CDD:302622
		PRMT5	53..430	CDD:282971	39/197 (20%)
		AdoMet_MTases	183..281	CDD:100107	23/122 (19%)
Mettl27	XP_006504585.1	AdoMet_MTases	31..>103	CDD:388410	12/45 (27%)
Mettl27	XP_006504585.1	Methyltransf_25	71..161	CDD:379312	19/96 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810