DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art4 and Ndufaf5

DIOPT Version :9

Sequence 1:	NP_001262445.1	Gene:	Art4 / 41219	FlyBaseID:	FBgn0037770	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_081369.2	Gene:	Ndufaf5 / 69487	MGIID:	1916737	Length:	343	Species:	Mus musculus

Alignment Length:	191	Identity:	40/191 - (20%)
Similarity:	70/191 - (36%)	Gaps:	54/191 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 QQQNMMQDYVRTSTYQR---AILGNAVDFQDKIVLDVGAGSGILSFFAVQAGAAKVYAIEASNMA 214
            |...|..||::.....|   .:...|.||  .:.||:|.|.|.::....:....|::   .:::|
Mouse    62 QPDPMKFDYLKEEVGSRIADRVYDIARDF--PLALDIGCGRGYIAQHLDKETVGKIF---QTDIA 121

  Fly   215 QYAQQ---------------------------LVESNNVQHKISVIPGKIEEIELPEKVDVIISE 252
            ::|.:                           ||.|:...|.::.:|..:|:|....|.|.:...
Mouse   122 EHALKNSLETDIPTVNILADEEFLPFQENTFDLVVSSLSLHWVNDLPRALEQIHYVLKPDGVFVG 186

  Fly   253 PM--GYMLYNER----MLETYLHARKWLKPQGKMYPTHGDLHIAPFSDESLYSEQYNKANF 307
            .|  |..||..|    :.||        :.:|...|     ||:||:..:.......:|.|
Mouse   187 AMFGGDTLYELRCSLQLAET--------EREGGFSP-----HISPFTAVNDLGHLLGRAGF 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art4	NP_001262445.1	PH-like	24..134	CDD:302622
		PRMT5	53..430	CDD:282971	40/191 (21%)
		AdoMet_MTases	183..281	CDD:100107	25/130 (19%)
Ndufaf5	NP_081369.2	BioC	93..310	CDD:273953	32/158 (20%)
Ndufaf5	NP_081369.2	Methyltransf_11	94..185	CDD:285453	17/93 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900