DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art4 and Alkbh8

DIOPT Version :9

Sequence 1:	NP_001262445.1	Gene:	Art4 / 41219	FlyBaseID:	FBgn0037770	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	XP_006509942.1	Gene:	Alkbh8 / 67667	MGIID:	1914917	Length:	709	Species:	Mus musculus

Alignment Length:	374	Identity:	67/374 - (17%)
Similarity:	127/374 - (33%)	Gaps:	107/374 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ARK--LATAASVSPLS------NCQFCGVVISSIADEQKLEFTNKYK------GSCTLL------ 53
            :||  |.|.....|:.      |..:..|:..:|.:.:|..||...|      |....|
Mouse   102 SRKQLLLTLEKCGPVEALLMPPNKPYAFVIFQTIEESKKAYFTLNGKEIIDDLGQKIFLYLNFVE 166

  Fly    54 -CSYDSQG---------VVLRVVSDDDRSHVLKEYMIAADTDAAQMGRRSYAVSL---------- 98
             ..:.:.|         ||..::|.::...:|:......||     |.:::..||
Mouse   167 KAQWKNMGLEALPPGLLVVEEIISSEEEKKLLESVNWTEDT-----GNQNFQRSLKHRRVKHFGY 226

  Fly    99 ---------DADNLVLRFASEQDQQLFRKVVEN--VKHLRPKSVFSQRTEESSASQYFQFYGYLS 152
                     |.|..:.....|....:..|:::.  :||         :.::.:.:||...:|
Mouse   227 EFHYESNTVDKDKPLPGGLPEVCSSILEKLLKEGYIKH---------KPDQLTINQYEPGHG--- 279

  Fly   153 QQQNMMQDYVRTSTYQRAILGNAVDFQDKIVLDVGAGSGILSFFAVQAGAAKVYAIEASNMAQYA 217
                 :..::.|.:          .|:|:|: .:..||.|:..|....|      :....|....
Mouse   280 -----IPAHIDTHS----------AFEDEII-SLSLGSAIVMDFKHPEG------VTVQVMLPRR 322

  Fly   218 QQLVESNNVQH--KISVIPGKIEEIELPEKV-DVIISEPMGYMLYNERMLETYLHARKWLK-PQG 278
            ..||.:...::  ...:.|.|.:.::..|:. ..||:..:|.:..::|.:.|....||..: |..
Mouse   323 SLLVMTGESRYLWTHGITPRKFDTVQASEQFKGGIITSDIGDLTLSKRGMRTSFTFRKVRRMPCN 387

  Fly   279 KMYPTHGDLH-------IAPFSDESLYSEQ------YNKANFWYQSAFH 314
            ..|.:..|..       :...|.|:|..||      ||:....:.|..|
Mouse   388 CSYSSVCDRQRKATPPSLTESSKEALELEQKHVHQVYNEIASHFSSTRH 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art4	NP_001262445.1	PH-like	24..134	CDD:302622	24/152 (16%)
		PRMT5	53..430	CDD:282971	54/316 (17%)
		AdoMet_MTases	183..281	CDD:100107	19/101 (19%)
Alkbh8	XP_006509942.1	DUF1891	46..82	CDD:117570
		RRM_ALKBH8	87..167	CDD:240877	14/64 (22%)
		2OG-FeII_Oxy	197..379	CDD:389772	35/220 (16%)
		Methyltransf_25	455..542	CDD:379312
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900