DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art4 and ANTKMT

DIOPT Version :9

Sequence 1:	NP_001262445.1	Gene:	Art4 / 41219	FlyBaseID:	FBgn0037770	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_076422.1	Gene:	ANTKMT / 65990	HGNCID:	14152	Length:	235	Species:	Homo sapiens

Alignment Length:	66	Identity:	16/66 - (24%)
Similarity:	32/66 - (48%)	Gaps:	14/66 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 VLDVGAGSGILSF----FAVQAGAAKV-YAIEASNMAQYAQQLVESNNVQHKISVI---PGKIEE 239
            :|...||||:.::    ..:|.|..:| ..::...:...|:|      |:|.:|::   |||..:
Human    23 LLQAAAGSGLAAYAVWALLLQPGFRRVPLRLQVPYVGASARQ------VEHVLSLLRGRPGKTVD 81

  Fly   240 I 240
            :
Human    82 L 82

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art4	NP_001262445.1	PH-like	24..134	CDD:302622
		PRMT5	53..430	CDD:282971	16/66 (24%)
		AdoMet_MTases	183..281	CDD:100107	16/66 (24%)
ANTKMT	NP_076422.1	N-terminal sequence (NTS). /evidence=ECO:0000303\|PubMed:31213526	1..22
		Methyltransferase (MTase). /evidence=ECO:0000303\|PubMed:31213526	43..77		8/39 (21%)
		Pre-methyltransferase (preMT). /evidence=ECO:0000303\|PubMed:31213526	43..77		8/39 (21%)
		HemK	<65..>123	CDD:225443	6/18 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	215..235
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900