DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Art4 and mettl7a.1

DIOPT Version :9

Sequence 1:	NP_001262445.1	Gene:	Art4 / 41219	FlyBaseID:	FBgn0037770	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_001073508.1	Gene:	mettl7a.1 / 569131	ZFINID:	ZDB-GENE-061027-239	Length:	242	Species:	Danio rerio

Alignment Length:	190	Identity:	39/190 - (20%)
Similarity:	77/190 - (40%)	Gaps:	44/190 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 YLSQQQNMMQDYVRTSTYQRAILGNAVDFQDKI----------------------VLDVGAGSGI 192
            |:::|..::..|.|  .:...:...:..:.||:                      :|:||.|||
Zfish    20 YIAEQAGLLSFYKR--VFPIIVYKISFSYNDKMNDKKRELFRNLDRFYPSKGSLRILEVGCGSG- 81

  Fly   193 LSFFAVQAGAAKVYAIEAS-NMAQYAQQLVESNNVQHKI--SVIPGKIEEIELPE--KVDVIISE 252
             :.|......:|:...:.: :..:|.::.:|.|  :|.:  |.|....|.::..|  .||.::..
Zfish    82 -ANFEHYPTGSKITCTDPNPHFKKYLEKSMEKN--EHLVYDSFIVASGENLQAVEDSSVDAVVCT 143

  Fly   253 PMGYMLYNERMLETYL-HARKWLKPQGKMYPTHGDLHIAPFSDES--LYSEQYNKANFWY 309
               .:|.:.:.....| .|::.|:|.|..:...   |:.  ||.|  :|..|:....|||
Zfish   144 ---LVLCSVKDTNKVLQEAKRVLRPGGAFFFLE---HVV--SDPSTWVYFFQHVLQPFWY 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art4	NP_001262445.1	PH-like	24..134	CDD:302622
		PRMT5	53..430	CDD:282971	39/190 (21%)
		AdoMet_MTases	183..281	CDD:100107	24/103 (23%)
mettl7a.1	NP_001073508.1	Methyltransf_11	74..171	CDD:369777	24/103 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900