DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art4 and alkbh8

DIOPT Version :9

Sequence 1:	NP_001262445.1	Gene:	Art4 / 41219	FlyBaseID:	FBgn0037770	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	XP_009290865.1	Gene:	alkbh8 / 556362	ZFINID:	ZDB-GENE-100922-251	Length:	666	Species:	Danio rerio

Alignment Length:	281	Identity:	58/281 - (20%)
Similarity:	92/281 - (32%)	Gaps:	65/281 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 EQKLEFTNKYKGSCTLLCSYDSQGVVLRVVSDDDRSHVLKEYMIAADTDAAQMGRRSYAVSLDAD 101
            |:|.....:.|.|.|||...|...|          ||..|..:::       .|.....||.::.
Zfish    12 EEKKLLRRQIKASHTLLKHEDITTV----------SHPTKHLVVS-------NGGLGNGVSRESL 59

  Fly   102 NLVLRFASEQDQQLFRKVVENVKHLRPKSVFSQRTEESSASQYFQFYGYLSQQQNMMQDYVRTST 166
            ..||:.....:..|       ....:|.:..|..:.|:..:.|....|...|    .||...|..
Zfish    60 LEVLKEGGTVESLL-------TPPSKPYAFVSYSSIEAGQNAYTLLNGRTLQ----CQDQTMTLY 113

  Fly   167 YQRAILGNAVDFQDKIVLDVGAGSGILSFF------------------AVQAGAAKVYAIEASNM 213
            :...:   .||....:...:..|..:|..|                  |....|.|  |::...:
Zfish   114 FSYVV---KVDCDRSVSCALPPGLSVLEDFVSLEEELQILKAVDWTPHADDVTAQK--ALKHRRV 173

  Fly   214 AQYAQQLVESNNVQHKISVIPGKIEEIELPEKVDVIISEPM--GYMLYNERMLETYLHARKWLKP 276
            ..|..:....||...|...:||     .||.:.|.::...:  |::    .:|...|...::...
Zfish   174 KHYGYEFRYDNNNVDKDKPLPG-----GLPVECDALLQRCLAGGHI----SVLPDQLTVNQYQSG 229

  Fly   277 QGKMYPTHGDLHIAPFSDESL 297
            ||  .|.|.|.| :||.|..|
Zfish   230 QG--IPPHVDTH-SPFEDTIL 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art4	NP_001262445.1	PH-like	24..134	CDD:302622	19/96 (20%)
		PRMT5	53..430	CDD:282971	52/265 (20%)
		AdoMet_MTases	183..281	CDD:100107	21/117 (18%)
alkbh8	XP_009290865.1	RRM_ALKBH8	40..119	CDD:240877	16/99 (16%)
		2OG-FeII_Oxy	130..300	CDD:304390	29/132 (22%)
		Methyltransf_11	409..498	CDD:285453
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900