DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art4 and zgc:162396

DIOPT Version :9

Sequence 1:	NP_001262445.1	Gene:	Art4 / 41219	FlyBaseID:	FBgn0037770	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_001038247.2	Gene:	zgc:162396 / 555292	ZFINID:	ZDB-GENE-030131-1190	Length:	271	Species:	Danio rerio

Alignment Length:	320	Identity:	66/320 - (20%)
Similarity:	120/320 - (37%)	Gaps:	91/320 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 QNMMQDYVRTSTYQR-------AILGNAVDFQDK-------IVLDVGAGSG-----ILSFFAVQA 200
            :.|.::....|.||:       .:....:.:.||       :.:|:|.|:|     :..:|
Zfish     3 ERMFEEKQHASLYQQYRFAPPDELKELILQYLDKKKGKPHQLAVDLGCGTGQTSRPLTPYF---- 63

  Fly   201 GAAKVYAIEASNMAQYAQQLVESNNVQ--HKISVIPGKIEEIELPE-KVDVIISEPMGYMLYNER 262
              .:|..|:.|.     .|:.|:..||  ..::...|..||:..|: .||::.:....:....||
Zfish    64 --QQVVGIDVSE-----SQVEEARAVQGFPNLTYRVGTAEELPFPDASVDLLTAASAAHWFDAER 121

  Fly   263 MLETYLHARKWLKPQGKMYPTHGDLHIAPFSDESLYSEQYNKANFWYQSAFHGVDLTTLHKEGMK 327
            .::   .|::.|||       ||.|.:..::|         .....::|.  |..|..:::|..:
Zfish   122 FVK---EAQRVLKP-------HGCLALFGYND---------SMKIHHESC--GDQLNIIYEELKQ 165

  Fly   328 EYFRQPIVDTFDIRICMA----KSVRHVCDFLNDKEDDLHLISIPLEFHILQTGICHGLAFWFDV 388
            |.  ||...|   ::..|    |.:..|..| .|||   .:.:||::   .|..:.:.|.|:
Zfish   166 EL--QPYTST---KVTGASTKLKDLFEVIPF-PDKE---RIETIPIK---EQLSVKNILGFF--- 215

  Fly   389 EFSGSSQNVWLSTSPTAPLTHWYQVRCLLPMPIFIKQGQTLTGRVLLEANRRQSYDVTID 448
             .:.|....:|..:|.|       ...||..          |...:||..:..|.|..:|
Zfish   216 -QTFSMYQAYLRANPKA-------ATALLEK----------TASRILEEIKATSTDAKVD 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art4	NP_001262445.1	PH-like	24..134	CDD:302622
		PRMT5	53..430	CDD:282971	60/300 (20%)
		AdoMet_MTases	183..281	CDD:100107	24/105 (23%)
zgc:162396	NP_001038247.2	Methyltransf_11	46..138	CDD:285453	27/112 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900