Protein Alignment Art4 and PRMT6

DIOPT Version :9

• Sequence 1: NP_001262445.1
• Gene: Art4 / 41219
• FlyBaseID: FBgn0037770
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_060607.2
• Gene: PRMT6 / 55170
• HGNCID: 18241
• Length: 375
• Species: Homo sapiens
• Alignment Length: 341
• Identity: 126/341 - (36%)
• Similarity: 176/341 - (51%)
• Gaps: 56/341 - (16%)

  Fly   127 RPKSVFSQRTEESSASQYFQFYGYLSQQQNMMQDYVRTSTYQRAILGNAVDFQDKIVLDVGAGSG 191
            ||:     ||:......|::.|..:|..:.|:.|.|||..|:..||.|....:.|.|||||||:|
Human    35 RPR-----RTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTG 94

  Fly   192 ILSFFAVQAGAAKVYAIEASNMAQYAQQLVESNNVQHKISVIPGKIEEIELPEKVDVIISEPMGY 256
            |||.|..||||.:|||:|||.:.|.|:::|..|.::.::.|:||.:|.:||||:||.|:||.|||
Human    95 ILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGY 159

  Fly   257 MLYNERMLETYLHAR-KWLKPQGKMYPTHGDLHIAPFSDESLYSEQYNKANFWYQSAFH-GVDLT 319
            .|.:|.||.:.|||| ||||..|.:.|...:|.|||.||:.|..    :..||.|...| |||::
Human   160 GLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEW----RLGFWSQVKQHYGVDMS 220

  Fly   320 TLHKEGMKEYFRQPIVDTFDIRICMAKSVRHVCDFLNDKEDDLHLISIPLEF-----------HI 373
            .|  ||            |..|..|..| ..|...|:.::    :::.|..|           ..
Human   221 CL--EG------------FATRCLMGHS-EIVVQGLSGED----VLARPQRFAQLELSRAGLEQE 266

  Fly   374 LQTGI-------C------HGLAFWFDVEFSG--SSQNVWLSTSPTAPLTHWYQVRCLLPMPIFI 423
            |:.|:       |      ||.|.||.|.|.|  |.:.:.|||||..|.|||.|....|..|:.:
Human   267 LEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQV 331

  Fly   424 KQGQTLTGRVLLEANR 439
            :|...::|.:.|..:|
Human   332 EQDTDVSGEITLLPSR 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Art4	NP_001262445.1	PH-like	24..134	CDD:302622	2/6 (33%)
		PRMT5	53..430	CDD:282971	123/330 (37%)
		AdoMet_MTases	183..281	CDD:100107	55/98 (56%)
PRMT6	NP_060607.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		2/7 (29%)
		AdoMet_MTases	67..>200	CDD:418430	68/132 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820