DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Art4 and Art9

DIOPT Version :9

Sequence 1:	NP_001262445.1	Gene:	Art4 / 41219	FlyBaseID:	FBgn0037770	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_650321.1	Gene:	Art9 / 41698	FlyBaseID:	FBgn0038188	Length:	313	Species:	Drosophila melanogaster

Alignment Length:	313	Identity:	75/313 - (23%)
Similarity:	134/313 - (42%)	Gaps:	42/313 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 NMMQDYVRTSTYQRAILGNAVDFQDKIVLDVGAGSGILSFFAVQAGAAKVYAIEASNMAQYAQQL 220
            :|:.|.:.|..|:.........|:||||||||..||:||..:|:|||.||.|:.....|::..:.
  Fly    14 SMLNDVISTRAYEWVFKRYERLFKDKIVLDVGCRSGLLSLMSVEAGAVKVMALGNRESAEFVSKA 78

  Fly   221 VESNNVQHKISVIPGKIEEIELP---EKVDVIISEPMGYMLYNERMLETYLHAR-KWLKPQGKMY 281
            ......:.....|.|.|.||.||   :|||:|:||.:|:.::.:.:.:..:.|| |||...|.:.
  Fly    79 FIGTEKEDIFEFIDGDIHEIVLPCGLKKVDIIVSEWVGHSVFVDSLFKEVIFAREKWLVKGGFII 143

  Fly   282 PTHGDLHIAPFSDESLYSEQYNKANFWYQSAFHGVDLTTLHKEGMKEYF---RQPIVDTF---DI 340
            |....|.:...:|   :..:..:.|...||.:.|..........:.|.:   .|.|.:.:   .|
  Fly   144 PNVAQLFVCGIAD---HPRKTVEVNILPQSDYPGRSYMVREPVSLIEDYVAKEQLITEKYLLKTI 205

  Fly   341 RICMAKSVRHVCDFLNDKEDDLHLISIPLEFHILQTGICHGLAFWFDV-------EFSGSSQNVW 398
            .:|.|    |:    ||:.     ..:|.:...|:......:..:.|:       :|     .:.
  Fly   206 DLCTA----HI----NDES-----FRVPFKLRGLRDSQLGAVVLYSDIGLCRPRGKF-----RLM 252

  Fly   399 LSTSPTAPLTHWYQVRCLLPMPIFIKQGQTLTGRVLL----EANRRQSYDVTI 447
            .||.|..|.|:..|....:..|:.:.:.:.:.|.:.:    :.:|...|..::
  Fly   253 FSTGPKRPRTYVRQTILFMDNPVEVAKCELVIGELGMYYKPDEHREVEYSFSL 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art4	NP_001262445.1	PH-like	24..134	CDD:302622
		PRMT5	53..430	CDD:282971	72/290 (25%)
		AdoMet_MTases	183..281	CDD:100107	37/101 (37%)
Art9	NP_650321.1	AdoMet_MTases	41..143	CDD:100107	37/101 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440095
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11006
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850