DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art4 and CG17807

DIOPT Version :9

Sequence 1:	NP_001262445.1	Gene:	Art4 / 41219	FlyBaseID:	FBgn0037770	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_611690.2	Gene:	CG17807 / 37585	FlyBaseID:	FBgn0034748	Length:	615	Species:	Drosophila melanogaster

Alignment Length:	277	Identity:	49/277 - (17%)
Similarity:	94/277 - (33%)	Gaps:	83/277 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LRPEEARKLATAASVSPLSNCQFCGVVISSIADEQKLEFTNKYKGSCTLLCSYDSQGVVLRVVSD 68
            :||:....:.:|:.          |:...:......|.|....||.|.  |||.:       :.|
  Fly   293 IRPKHIDVVPSASG----------GLTTQARGKRTSLTFRRLRKGPCD--CSYPA-------LCD 338

  Fly    69 DDRSHVLKEYMIAADTDAAQMGRRSYAVSLDADNLVLRFASEQDQQLFRKVVENVKHLRPKSVFS 133
            ..::.|.:|...:.   |||      |::|:..|:         .:::.|:.::         ||
  Fly   339 TQQTKVPQELHASL---AAQ------AITLEQQNV---------HEVYDKIADH---------FS 376

  Fly   134 QRTEESSASQYFQFYGYLSQQQNMMQDYVRTSTYQRAILGNAVDFQDKIVLDVGAGSGILSFFAV 198
            : |..:...|..:|......|                          .:|||:|.|:|  .:.:.
  Fly   377 E-TRHTPWPQVSEFLDSFEPQ--------------------------SVVLDIGCGNG--KYLSC 412

  Fly   199 QAGAAKVYAIEASNMAQYAQQLVESNNV-QHKISVIPGKIEEIELPEKVDVIISEPMGYMLYNER 262
            ......|....|..:....::  :..|| :....|:|.:...|:....:.||     .::...||
  Fly   413 NPLLLSVGCDRAQGLLAVGRR--KGQNVFRCDCLVVPVRSSSIDGCISIAVI-----HHLATKER 470

  Fly   263 MLETYLHARKWLKPQGK 279
            .|.......:.|:|.|:
  Fly   471 RLAALQEMARVLRPGGR 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art4	NP_001262445.1	PH-like	24..134	CDD:302622	20/109 (18%)
		PRMT5	53..430	CDD:282971	40/228 (18%)
		AdoMet_MTases	183..281	CDD:100107	21/98 (21%)
CG17807	NP_611690.2	RRM_ALKBH8	40..119	CDD:240877
		2OG-FeII_Oxy	136..322	CDD:304390	5/38 (13%)
		Methyltransf_11	400..490	CDD:285453	20/97 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900