DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art4 and Mettl7b

DIOPT Version :9

Sequence 1:	NP_001262445.1	Gene:	Art4 / 41219	FlyBaseID:	FBgn0037770	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_001019447.1	Gene:	Mettl7b / 366792	RGDID:	1305205	Length:	244	Species:	Rattus norvegicus

Alignment Length:	189	Identity:	34/189 - (17%)
Similarity:	72/189 - (38%)	Gaps:	62/189 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 QDYVRTSTYQRAILGNAVDFQ----DKIVLDVGAGSGILSFFAVQAGAAKVYAIEAS-NMAQY-A 217
            :.|.:..:.:|.:.....|.:    :..:|::|.|:|  :.|.......||..::.: |..:: .
  Rat    46 RSYKKMESKKRELFSQIKDLKGTSNEVTLLELGCGTG--ANFQFYPPGCKVTCVDPNPNFEKFLT 108

  Fly   218 QQLVESNNVQHKISVI----------------------------PGKI-EEIELPEKVDVI---- 249
            :.:.|:.::|::..::                            |.|: :|::...|...:
  Rat   109 KSMAENRHLQYERFIVAYGENMKQLADSSMDVVVCTLVLCSVQSPRKVLQEVQRVLKPGGLLFFW 173

  Fly   250 --ISEPMG-YMLYNERMLE-TYLH-------ARKWLKPQGKMYPTHGDLHIAPFSDESL 297
              :|||.| ..|..:|:|| |:.|       .|:          |..|:..|.||:..|
  Rat   174 EHVSEPQGSQALLWQRVLEPTWKHIGDGCHLTRE----------TWKDIEKAQFSEVQL 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art4	NP_001262445.1	PH-like	24..134	CDD:302622
		PRMT5	53..430	CDD:282971	34/189 (18%)
		AdoMet_MTases	183..281	CDD:100107	25/143 (17%)
Mettl7b	NP_001019447.1	Methyltransf_11	75..172	CDD:285453	14/98 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900