DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art4 and Art8

DIOPT Version :9

Sequence 1:	NP_001262445.1	Gene:	Art4 / 41219	FlyBaseID:	FBgn0037770	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_609478.1	Gene:	Art8 / 34528	FlyBaseID:	FBgn0032329	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	303	Identity:	113/303 - (37%)
Similarity:	159/303 - (52%)	Gaps:	53/303 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 ASQYFQFYGYLSQQQNMMQDYVRTSTYQRAILGNAVDFQDKIVLDVGAGSGILSFFAVQAGAAKV 205
            |:.||..|..|...:.|::|..|...|..|||||...|:||||:|||||:||||.|..:|||..|
  Fly     2 ANTYFDEYENLEIHELMLKDRPRQEAYYNAILGNKDLFKDKIVMDVGAGTGILSAFCAKAGARLV 66

  Fly   206 YAIEASNMA-QYAQQLVESNNVQHKISVIPGKIEEIELP---EKVDVIISEPMGYMLYNERMLET 266
            ||:||||:| :.|..|:|.|.:.:.:.||..::||..||   ||||:|:||.||:.|.:|.||::
  Fly    67 YAVEASNVATKVALDLIEDNGLTNVVKVIQSRVEEFVLPAEAEKVDIIVSEWMGFYLLHEGMLDS 131

  Fly   267 YLHAR-KWLKPQGKMYPTHGDLHIAPFSDESLYSEQYNKANFWYQSAFHGVDLTTLHKEGMKEYF 330
            .|.|| |:||..|.::|:...:.:||.|..||:.:       |     |.||       |:|
  Fly   132 VLLARDKFLKEGGLLFPSECTIFVAPCSVPSLFDD-------W-----HNVD-------GIK--- 174

  Fly   331 RQPIVDTFDIRICMAKSVR------------------HVCDFLNDKEDDLHLISIPLEFHILQTG 377
                :|||..::...||.|                  |..:.|:.:..||..|.........:.|
  Fly   175 ----MDTFARKLRTQKSSRPEITQLNPQDLLHEGVVFHWMNLLDVEASDLDSIQFKEVITAQKAG 235

  Fly   378 ICHGLAFWFDVEFSGSSQNVWLSTSPTAPLTHWYQVRCLLPMP 420
            ...|...||||:|.|  ::..|||||.:|.|||.|  |::.:|
  Fly   236 NHQGFCIWFDVQFPG--EDFVLSTSPLSPPTHWKQ--CVVVLP 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art4	NP_001262445.1	PH-like	24..134	CDD:302622
		PRMT5	53..430	CDD:282971	113/303 (37%)
		AdoMet_MTases	183..281	CDD:100107	52/102 (51%)
Art8	NP_609478.1	SmtA	1..244	CDD:223574	95/267 (36%)
Art8	NP_609478.1	Methyltransf_18	40..147	CDD:289607	55/106 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440087
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11006
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850