Protein Alignment Art4 and PRMT1

DIOPT Version :10

• Sequence 1: NP_649963.1
• Gene: Art4 / 41219
• FlyBaseID: FBgn0037770
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001527.3
• Gene: PRMT1 / 3276
• HGNCID: 5187
• Length: 371
• Species: Homo sapiens
• Alignment Length: 376
• Identity: 129/376 - (34%)
• Similarity: 200/376 - (53%)
• Gaps: 29/376 - (7%)

  Fly   101 DNLVLRFASEQDQQLFRKVVENVKHLRPKSVFSQRTEE-SSASQYFQFYGYLSQQQNMMQDYVRT 164
            :|.|...|:....|   ..:|.|...:.:|......|: :|...||..|.:....:.|::|.|||
Human    12 ENFVATLANGMSLQ---PPLEEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRT 73

  Fly   165 STYQRAILGNAVDFQDKIVLDVGAGSGILSFFAVQAGAAKVYAIEASNMAQYAQQLVESNNVQHK 229
            .||:.::..|...|:||:|||||:|:|||..||.:|||.||..||.|:::.||.::|::|.:.|.
Human    74 LTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHV 138

  Fly   230 ISVIPGKIEEIELP-EKVDVIISEPMGYMLYNERMLETYLHAR-KWLKPQGKMYPTHGDLHIAPF 292
            :::|.||:||:||| ||||:||||.|||.|:.|.||.|.|:|| |||.|.|.::|....|::...
Human   139 VTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLYVTAI 203

  Fly   293 SDESLYSEQYNKANF-WYQSAFHGVDLTTLHKEGMKEYFRQPIVDTFD-----IRICMAKSVRHV 351
            .|     .||..... |:::.: |.|::.:....:||    |:||..|     ...|:.|.|
Human   204 ED-----RQYKDYKIHWWENVY-GFDMSCIKDVAIKE----PLVDVVDPKQLVTNACLIKEV--- 255

  Fly   352 CDFLNDKEDDLHLISIPLEFHILQTGICHGLAFWFDVEFSGSSQNVWLSTSPTAPLTHWYQVRCL 416
             |....|.:||...| |....:.:....|.|..:|::||:...:....||||.:|.|||.|....
Human   256 -DIYTVKVEDLTFTS-PFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFY 318

  Fly   417 LPMPIFIKQGQTLTGRVLLEANRRQSYDV--TIDLHIEGTLISSSNTLDLK 465
            :...:.:|.|:.:.|.:.:..|.:.:.|:  ||||..:|.|...|.:.|.:
Human   319 MEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYR 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Art4	NP_649963.1	PH-like	24..134	CDD:473070	7/32 (22%)
		COG4076	154..341	CDD:443253	81/194 (42%)
PRMT1	NP_001527.3	COG4076	63..>236	CDD:443253	77/182 (42%)