DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art4 and Mettl7a

DIOPT Version :9

Sequence 1:	NP_001262445.1	Gene:	Art4 / 41219	FlyBaseID:	FBgn0037770	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_001032432.1	Gene:	Mettl7a / 315306	RGDID:	1308407	Length:	244	Species:	Rattus norvegicus

Alignment Length:	170	Identity:	38/170 - (22%)
Similarity:	69/170 - (40%)	Gaps:	31/170 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   165 STYQRAILGNAVDF---QDKI-VLDVGAGSGILSFFAVQAGAAKVYAIEAS-NMAQYA-QQLVES 223
            :|.:|.:..|..:|   ..|: :|:||.|:|  :.|.......:|..|:.: |..::. :.:.|:
  Rat    52 ATRKRELFSNLQEFAGPSGKLSLLEVGCGTG--ANFKFYPPGCRVTCIDPNPNFEKFLFKSVAEN 114

  Fly   224 NNVQ-HKISVIPGKIEEIELPEKVDVIISEPMGYMLYNERMLETYL-HARKWLKPQGKMYPTHGD 286
            .::| .:..|..|:.........|||::..   .:|.:.:..|..| ...:.|:|.|..|...
  Rat   115 RHLQFERFLVAVGEDMHQVADGSVDVVVCT---LVLCSVKSQEKILREVCRVLRPGGAFYFME-- 174

  Fly   287 LHIAPFSDESLYSEQYNKANFWYQ-------SAFHGVDLT 319
             |:|        .|:.....||.|       ..|.|.:||
  Rat   175 -HVA--------DERSTWNYFWQQVLDPVWFLVFDGCNLT 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art4	NP_001262445.1	PH-like	24..134	CDD:302622
		PRMT5	53..430	CDD:282971	38/170 (22%)
		AdoMet_MTases	183..281	CDD:100107	22/101 (22%)
Mettl7a	NP_001032432.1	Methyltransf_11	75..172	CDD:400514	22/101 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900