Protein Alignment Glut4EF and SLC2A4RG

DIOPT Version :9

• Sequence 1: NP_001262443.1
• Gene: Glut4EF / 41217
• FlyBaseID: FBgn0267336
• Length: 950
• Species: Drosophila melanogaster
• Sequence 2: NP_064446.2
• Gene: SLC2A4RG / 56731
• HGNCID: 15930
• Length: 387
• Species: Homo sapiens
• Alignment Length: 568
• Identity: 120/568 - (21%)
• Similarity: 165/568 - (29%)
• Gaps: 287/568 - (50%)

  Fly   217 RLADMSGERR--------RTTTHSIEVPSQLTAQHNSRKRPPSDHQDYGNYLETCRAAEILSSMK 273
            |.:|:...|.        ||.:..|.||:|......:|             |:...||..|:|:.
Human    64 RASDLGAPRTWTGAAAGPRTPSAHIPVPAQRATPGKAR-------------LDEVMAAAALTSLS 115

  Fly   274 -----LQSPHGSMADK----------CSSPGSSSSAS------W-------SSGSPSPPLSDDGH 310
                 |.:|..:.:.:          ...|||.||:|      |       |..:|||||..:.
Human   116 TSPLLLGAPVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPLPPEA- 179

  Fly   311 AHHSPHNIMSPHDADNARTRTASVSTSDEGIVIDYKEERKKKSK---KFRCVYRGCVGVVDDLNG 372
            ||                            .:......||:||.   .|:|:::.|..|:...:.
Human   180 AH----------------------------FLFGEPTLRKRKSPAQVMFQCLWKSCGKVLSTASA 216

  Fly   373 VVRHIRKTHLGKDSHRSADDDGNEEDFYLEDADDDVEQVKPTLAS----EPTLSHRDMARPPHED 433
            :.||||..|||:.:.....|  .|||||..:.|..|:.:...|:|    .||.| ...|.|..|.
Human   217 MQRHIRLVHLGRQAEPEQSD--GEEDFYYTELDVGVDTLTDGLSSLTPVSPTAS-MPPAFPRLEL 278

  Fly   434 PEYQKQIVGNFKQGRGGSHYNHLAQSHGRTISGSNIPSTHQQQLQNNNTSCIPTSHLAHHNYTCP 498
            ||..:                                                           |
Human   279 PELLE-----------------------------------------------------------P 284

  Fly   499 AATATVGSYSSTGTGSVAASSSASPIGKHARSSSSRPTHSVAPYPSPTYVQQQQHHQHTHHHNYA 563
            .|.                   .||:         ||  ...|.|.|
Human   285 PAL-------------------PSPL---------RP--PAPPLPPP------------------ 301

  Fly   564 GSSGSSNSSSSSSPVIHSNSSANNMLQQLSQQNVTVTAHHSQQQQQLQQQQHHQQQQQHSHQQQQ 628
                         ||:  ::.||                               .|..||.:..|
Human   302 -------------PVL--STVAN-------------------------------PQSCHSDRVYQ 320

  Fly   629 QHLLSSVTITPNFHPAQQQHHHQPMRGHQQQHPQTTAGNMVAQNNSNNHSNGSNPLQQQQHMAQQ 693
            ..|.          ||:.:             ||.|             ..|:.|    ..::.:
Human   321 GCLT----------PARLE-------------PQPT-------------EVGACP----PALSSR 345

  Fly   694 VAVKHTPHSPGKRTRGENKKCRKVYGMEKRDQWCTQCRWKKACSRFGD 741
            :.|  |...|    ||:.||||||||||:||.|||.|||||||.||.|
Human   346 IGV--TLRKP----RGDAKKCRKVYGMERRDLWCTACRWKKACQRFLD 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut4EF	NP_001262443.1	DUF4772	<123..177	CDD:292616
SLC2A4RG	NP_064446.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..97		9/32 (28%)
		PRK12323	<2..>198	CDD:237057	36/175 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	139..179		13/39 (33%)
		Nuclear export signal	253..263		2/9 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	283..305		11/143 (8%)
		Nuclear localization signal. /evidence=ECO:0000305	351..354		1/6 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144533
Domainoid	1	1.000	138	1.000	Domainoid score	I4845
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D390760at33208
OrthoFinder	1	1.000	-	-		FOG0001758
OrthoInspector	1	1.000	-	-		otm41462
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13006
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1285
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	7.040