Protein Alignment Glut4EF and Zfp395

DIOPT Version :9

• Sequence 1: NP_001262443.1
• Gene: Glut4EF / 41217
• FlyBaseID: FBgn0267336
• Length: 950
• Species: Drosophila melanogaster
• Sequence 2: NP_950194.2
• Gene: Zfp395 / 380912
• MGIID: 2682318
• Length: 508
• Species: Mus musculus
• Alignment Length: 780
• Identity: 178/780 - (22%)
• Similarity: 266/780 - (34%)
• Gaps: 318/780 - (40%)

  Fly     5 RRLAKRSIIGTKVCAKGPDGLWYSGTISDVKTPPSYSGPLSPPPPPTFVVPGEAPINADTRYLVR 69
            |||.|||::|.:|.  ||         |..:.|...:.||.|
Mouse     4 RRLGKRSLLGARVL--GP---------SAAEVPSGATLPLEP----------------------- 34

  Fly    70 FDFKTAVESPTATTSSAASTSSTSSTDPSVIVETRRAANVHISPAQALRRSAMIKEFRESDLIGP 134
                 .:|.|    ..|.|.|..:|.|| |..|         .|.:.|:              ..
Mouse    35 -----QIEVP----EGAMSLSPLTSKDP-VCQE---------QPKELLK--------------AL 66

  Fly   135 GFRSIMDTELQPGQRVYFTYNGREQSGDVVKHDATKDEVIVKITTVGNEEPIELKKRLEEVRLLE 199
            |.........||||:|...|.|:|..|.|.:|...:|:|.|::.    ::.::::.::|||.|.|
Mouse    67 GTSGHPQVAFQPGQKVCVWYGGQECKGLVEQHSWAEDKVTVRLL----DQKLQIRCKVEEVWLAE 127

  Fly   200 SRRSARLADQDRDTDFARLADMSGERRRTTTH--SIEVPSQLTAQHNSRKRPPSDHQDYGN---- 258
            .:.||                         :|  ::|..:|:.|.     ||.|.:.|...
Mouse   128 LQGSA-------------------------SHVPALEPGAQVPAY-----RPVSRNIDVPKRKSD 162

  Fly   259 --YLETCRAAEILSSMK----LQSPHGS----------------MADKCSSPGSSSSASWSSGS- 300
              .::...||.:|:|:.    :|||.|:                .:...|..|||...|.||||
Mouse   163 AVEMDEMMAAMVLTSLSCSPVVQSPPGAEPIFSVSRAACGDLWKESGDVSDSGSSGHWSGSSGSS 227

  Fly   301 -PSPPLSDDGHAHHSPHNIMSPHDADNARTRTASVSTSDEGIVIDYKEERKKKSK---KFRCVYR 361
             ||||     |...||..:   .||..:........|..:..::|....||:::.   .::|::.
Mouse   228 TPSPP-----HPQASPKYL---GDAFGSPQTDHGFETDPDPFLLDEPAPRKRRNSVKVMYKCLWP 284

  Fly   362 GCVGVVDDLNGVVRHIRKTHLGK--DSHRSADDDGNEEDFYLEDADDDVEQVKPTLASEPTLSHR 424
            .|..|:..:.|:.||::..|||.  ||    |....|||||..:.     |:|..       |.:
Mouse   285 SCGKVLRSIVGIKRHVKALHLGDTVDS----DQFKREEDFYYTEM-----QMKEE-------SAQ 333

  Fly   425 DMARPPHEDPEYQKQIVGNFKQGRGGSHYNHLAQSHGRTISGSNIPSTHQQQLQNNNTSCIPTSH 489
            .:|.||                                      .|.|...:
Mouse   334 AVAAPP--------------------------------------APGTPMGE------------- 347

  Fly   490 LAHHNYTCPAATATVGSYSSTGTGSVAASSSASPIGKHARSSSSRPTHSVAPYPSPTYVQQQQHH 554
                    ||:|:.|.|.|       .|:.|..|    |:..||.|.|     |.
Mouse   348 --------PASTSRVTSPS-------LAALSLPP----AKVQSSGPEH-----PG---------- 378

  Fly   555 QHTHHHNYAGSSGSSNSSSSSSPVIHSNSSANNMLQQLSQQNVTVTAHHSQQQQQLQQQQHHQQQ 619
                    ..||..|.:.|.|:|....:..|::..|.|....:.|:
Mouse   379 --------LESSLPSVALSKSAPGSFWHIQADHAYQALPSFQIPVS------------------- 416

  Fly   620 QQHSHQQQQQHLLSSV------TITPNFHPAQQQ--HHHQPMRGHQQQHPQTTAGNMVAQNNSNN 676
                     .|:.:|:      |.|.:..|.:.:  ...:|     ||.|.|...:::.
Mouse   417 ---------PHIYTSISWAAAPTTTSSLSPVRSRSLSFSEP-----QQPPPTVKSHLIV------ 461

  Fly   677 HSNGSNPLQQQQHMAQQVAVKHTPHSPGKRTRGENKKCRKVYGMEKRDQWCTQCRWKKACSRFGD 741
                ::|.:.|              |..::.|||.||||||||:|.||||||.|||||||.||.|
Mouse   462 ----TSPPRAQ--------------SSTRKARGEAKKCRKVYGIEHRDQWCTACRWKKACQRFLD 508

  Fly   742  741
            Mouse   509  508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut4EF	NP_001262443.1	DUF4772	<123..177	CDD:292616	15/53 (28%)
Zfp395	NP_950194.2	DUF4772	4..110	CDD:374280	42/172 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834657
Domainoid	1	1.000	142	1.000	Domainoid score	I4673
eggNOG	1	0.900	-	-		E1_28PJI
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	142	1.000	Inparanoid score	I4456
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D390760at33208
OrthoFinder	1	1.000	-	-		FOG0001758
OrthoInspector	1	1.000	-	-		otm43513
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13006
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5442
SonicParanoid	1	1.000	-	-		X1285
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.020