DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9458 and Elovl4

DIOPT Version :9

Sequence 1:	NP_731419.1	Gene:	CG9458 / 41214	FlyBaseID:	FBgn0037765	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_683743.2	Gene:	Elovl4 / 83603	MGIID:	1933331	Length:	312	Species:	Mus musculus

Alignment Length:	263	Identity:	92/263 - (34%)
Similarity:	138/263 - (52%)	Gaps:	48/263 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PLLASHKPVLMVLATYLFFVKIAGPKIMRNRKPFDLRGLIKAYNIMQIVYNVIMCFFAVHFMLGP 84
            ||:.|..|.:.:...||.||.: |||.|::|:||.:|.::..||...::.|:.:  |...||
Mouse    41 PLMQSPWPTISISTLYLLFVWL-GPKWMKDREPFQMRLVLIIYNFGMVLLNLFI--FRELFM--- 99

  Fly    85 GDYN----FKCIKNLPPDHEYKT-----------WERWLTYSYFFNKLLDLLETVFFVLRKKDRQ 134
            |.||    :.|     ...:|..           |  |    ||.:|.::.|:||||:||||:.|
Mouse   100 GSYNAGYSYIC-----QSVDYSNDVNEVRIAGALW--W----YFVSKGVEYLDTVFFILRKKNNQ 153

  Fly   135 ISFLHVFHHMYMLYFSFMYLYYYGY----GGHGFFMCFFNVVVHIMMYSYYYQSSLNRDSKGDLW 195
            :|||||:||..|     ..|::.|.    ||..||....|..:|::|||||..::.....:..||
Mouse   154 VSFLHVYHHCTM-----FTLWWIGIKWVAGGQAFFGAQMNSFIHVIMYSYYGLTAFGPWIQKYLW 213

  Fly   196 WKKYITIVQLIQFGIVLGH---SIYTLKQPDCPSARFSATCAGSISVVFIILFSNFYFHAYIRPK 257
            ||:|:|::||:||.:.:||   |:||    |||..::......:.::.||.||.|||...|..||
Mouse   214 WKRYLTMLQLVQFHVTIGHTALSLYT----DCPFPKWMHWALIAYAISFIFLFLNFYTRTYNEPK 274

  Fly   258 KRK 260
            :.|
Mouse   275 QSK 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9458	NP_731419.1	ELO	20..261	CDD:279492	92/263 (35%)
Elovl4	NP_683743.2	ELO	41..277	CDD:279492	91/261 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	273..312		3/5 (60%)
		Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03204, ECO:0000269\|PubMed:24569140	308..312
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820