DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9458 and ELOVL4

DIOPT Version :9

Sequence 1:	NP_731419.1	Gene:	CG9458 / 41214	FlyBaseID:	FBgn0037765	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_073563.1	Gene:	ELOVL4 / 6785	HGNCID:	14415	Length:	314	Species:	Homo sapiens

Alignment Length:	261	Identity:	97/261 - (37%)
Similarity:	141/261 - (54%)	Gaps:	44/261 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PLLASHKPVLMVLATYLFFVKIAGPKIMRNRKPFDLRGLIKAYNIMQIVYNVIMCFFAVHFMLGP 84
            ||:.|..|.|.:...||.||.: |||.|::|:||.:|.::..||...::.|:.:  |...||
Human    41 PLMQSPWPTLSISTLYLLFVWL-GPKWMKDREPFQMRLVLIIYNFGMVLLNLFI--FRELFM--- 99

  Fly    85 GDYN----FKC-----IKNLPPDHEYK----TWERWLTYSYFFNKLLDLLETVFFVLRKKDRQIS 136
            |.||    :.|     ..|:   ||.:    .|  |    ||.:|.::.|:||||:||||:.|:|
Human   100 GSYNAGYSYICQSVDYSNNV---HEVRIAAALW--W----YFVSKGVEYLDTVFFILRKKNNQVS 155

  Fly   137 FLHVFHHMYMLYFSFMYLYYYGY----GGHGFFMCFFNVVVHIMMYSYYYQSSLNRDSKGDLWWK 197
            ||||:||..|     ..|::.|.    ||..||....|..:|::|||||..::.....:..||||
Human   156 FLHVYHHCTM-----FTLWWIGIKWVAGGQAFFGAQLNSFIHVIMYSYYGLTAFGPWIQKYLWWK 215

  Fly   198 KYITIVQLIQFGIVLGH---SIYTLKQPDCPSARFSATCAGSISVVFIILFSNFYFHAYIRPKKR 259
            :|:|::|||||.:.:||   |:||    |||..::......:.::.||.||.|||...|..|||.
Human   216 RYLTMLQLIQFHVTIGHTALSLYT----DCPFPKWMHWALIAYAISFIFLFLNFYIRTYKEPKKP 276

  Fly   260 K 260
            |
Human   277 K 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9458	NP_731419.1	ELO	20..261	CDD:279492	97/261 (37%)
ELOVL4	NP_073563.1	ELO	41..278	CDD:279492	97/261 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	275..314		2/3 (67%)
		Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03204	310..314
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820