DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9458 and ELOVL1

DIOPT Version :9

Sequence 1:	NP_731419.1	Gene:	CG9458 / 41214	FlyBaseID:	FBgn0037765	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_001243328.1	Gene:	ELOVL1 / 64834	HGNCID:	14418	Length:	279	Species:	Homo sapiens

Alignment Length:	264	Identity:	97/264 - (36%)
Similarity:	141/264 - (53%)	Gaps:	51/264 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PLLASHKPVLM--VLATYLFFVKIAGPKIMRNRKPFDLRGLIKAYNI------MQIVYNVIMCFF 76
            ||:.|  |:||  :|.||::||...||:||.|||||.|||.:..||.      :.|||..:|..:
Human    23 PLMGS--PLLMTSILLTYVYFVLSLGPRIMANRKPFQLRGFMIVYNFSLVALSLYIVYEFLMSGW 85

  Fly    77 AVHFMLGPGDYNFKCIKNLPPDH----EYKTWER--WLTYSYFFNKLLDLLETVFFVLRKKDRQI 135
            .       ..|.::|.   |.|:    |.....|  ||   :.|:|.::|::||.|:|||||.|:
Human    86 L-------STYTWRCD---PVDYSNSPEALRMVRVAWL---FLFSKFIELMDTVIFILRKKDGQV 137

  Fly   136 SFLHVFHHMYMLYFSFMYLYYYGYGGHGFFMCFFNVVVHIMMYSYYYQSSLNRDSKGDLWWKKYI 200
            :|||||||. :|.:|:.:......||.|.|....|..||::||.||..|:....::..|||||::
Human   138 TFLHVFHHS-VLPWSWWWGVKIAPGGMGSFHAMINSSVHVIMYLYYGLSAFGPVAQPYLWWKKHM 201

  Fly   201 TIVQLIQFGIVLGH-SIYTLKQPDCPSARFSATCAGSISV----------VFIILFSNFYFHAYI 254
            |.:|||||.:|..| |.|          .|.::|.....|          :|.:|||||::|:|.
Human   202 TAIQLIQFVLVSLHISQY----------YFMSSCNYQYPVIIHLIWMYGTIFFMLFSNFWYHSYT 256

  Fly   255 RPKK 258
            :.|:
Human   257 KGKR 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9458	NP_731419.1	ELO	20..261	CDD:279492	97/264 (37%)
ELOVL1	NP_001243328.1	ELO	23..260	CDD:307345	96/262 (37%)
ELOVL1	NP_001243328.1	Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03201	275..279
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11157
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.920