DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16904 and Elovl4

DIOPT Version :9

Sequence 1:	NP_649957.1	Gene:	CG16904 / 41212	FlyBaseID:	FBgn0037763	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_683743.2	Gene:	Elovl4 / 83603	MGIID:	1933331	Length:	312	Species:	Mus musculus

Alignment Length:	267	Identity:	99/267 - (37%)
Similarity:	144/267 - (53%)	Gaps:	28/267 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VFDKPFADPVQLPLAGSIRTSVIIITVYLLFVLKLGRKLMDKHEALQLRGVLKFYNIGQVLFNSV 68
            :.||..||   .||..|...::.|.|:|||||. ||.|.|...|..|:|.||..||.|.||.|..
Mouse    32 IADKRVAD---WPLMQSPWPTISISTLYLLFVW-LGPKWMKDREPFQMRLVLIIYNFGMVLLNLF 92

  Fly    69 IFVWGIHLLFV---QKPYNLSCMQVLPQDHELKSTERTLS---YMYHLNKVLDLMDTIFFVLRKK 127
            ||    ..||:   ...|:..|..|   |:.....|..::   :.|.::|.::.:||:||:||||
Mouse    93 IF----RELFMGSYNAGYSYICQSV---DYSNDVNEVRIAGALWWYFVSKGVEYLDTVFFILRKK 150

  Fly   128 QRQITFLHVFHHVFMVFTSHMLIRFYGFGGHVFLICMFNVLVHIVMYGYYYASSQSQNVQESLWW 192
            ..|::||||:||..| ||...:...:..||..|.....|..:|::||.||..::....:|:.|||
Mouse   151 NNQVSFLHVYHHCTM-FTLWWIGIKWVAGGQAFFGAQMNSFIHVIMYSYYGLTAFGPWIQKYLWW 214

  Fly   193 KKYLTLGQLVQFLLMFLH---CMYTYFQPNCSASRGVIY-VISSASAFMFLMFTKFYIKTYIRPK 253
            |:|||:.|||||.:...|   .:||    :|...:.:.: :|:.|.:|:|| |..||.:||..||
Mouse   215 KRYLTMLQLVQFHVTIGHTALSLYT----DCPFPKWMHWALIAYAISFIFL-FLNFYTRTYNEPK 274

  Fly   254 EVKSKGK 260
            :.|: ||
Mouse   275 QSKT-GK 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16904	NP_649957.1	ELO	16..257	CDD:279492	92/250 (37%)
Elovl4	NP_683743.2	ELO	41..277	CDD:279492	92/249 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	273..312		5/9 (56%)
		Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03204, ECO:0000269\|PubMed:24569140	308..312
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820