DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16904 and ELOVL1

DIOPT Version :9

Sequence 1:	NP_649957.1	Gene:	CG16904 / 41212	FlyBaseID:	FBgn0037763	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001243328.1	Gene:	ELOVL1 / 64834	HGNCID:	14418	Length:	279	Species:	Homo sapiens

Alignment Length:	267	Identity:	90/267 - (33%)
Similarity:	140/267 - (52%)	Gaps:	29/267 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 ADP-VQ-LPLAGS--IRTSVIIITVYLLFVLKLGRKLMDKHEALQLRGVLKFYNIGQVLFNSVIF 70
            ||| :| .||.||  :.||:::..||  |||.||.::|...:..||||.:..||...|.. |:..
Human    15 ADPRIQGYPLMGSPLLMTSILLTYVY--FVLSLGPRIMANRKPFQLRGFMIVYNFSLVAL-SLYI 76

  Fly    71 VWGIHLLFVQKPYNLSCMQVLPQDHELKSTER----TLSYMYHLNKVLDLMDTIFFVLRKKQRQI 131
            |:...:......|...|.   |.|:. .|.|.    .:::::..:|.::||||:.|:||||..|:
Human    77 VYEFLMSGWLSTYTWRCD---PVDYS-NSPEALRMVRVAWLFLFSKFIELMDTVIFILRKKDGQV 137

  Fly   132 TFLHVFHHVFMVFTSHMLIRFYGF----GGHVFLICMFNVLVHIVMYGYYYASSQSQNVQESLWW 192
            ||||||||..:.::     .::|.    ||......|.|..||::||.||..|:.....|..|||
Human   138 TFLHVFHHSVLPWS-----WWWGVKIAPGGMGSFHAMINSSVHVIMYLYYGLSAFGPVAQPYLWW 197

  Fly   193 KKYLTLGQLVQFLLMFLHCMYTYFQPNCSASRGV-IYVISSASAFMFLMFTKFYIKTYIR----P 252
            ||::|..||:||:|:.||....||..:|:....| |::|.......|::|:.|:..:|.:    |
Human   198 KKHMTAIQLIQFVLVSLHISQYYFMSSCNYQYPVIIHLIWMYGTIFFMLFSNFWYHSYTKGKRLP 262

  Fly   253 KEVKSKG 259
            :.::..|
Human   263 RALQQNG 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16904	NP_649957.1	ELO	16..257	CDD:279492	85/255 (33%)
ELOVL1	NP_001243328.1	ELO	23..260	CDD:307345	84/248 (34%)
ELOVL1	NP_001243328.1	Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03201	275..279
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11157
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.920