DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eloF and Elovl4

DIOPT Version :9

Sequence 1:	NP_649956.1	Gene:	eloF / 41211	FlyBaseID:	FBgn0037762	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_683743.2	Gene:	Elovl4 / 83603	MGIID:	1933331	Length:	312	Species:	Mus musculus

Alignment Length:	261	Identity:	89/261 - (34%)
Similarity:	139/261 - (53%)	Gaps:	36/261 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 PVVSNPWITMGTLIGYLLFVLKLGPKIMEHRKPFHLNGVIRIYNIFQILYNGLILVLGVHFLFVL 75
            |::.:||.|:.....|||||. ||||.|:.|:||.:..|:.|||...:|.|          ||:.
Mouse    41 PLMQSPWPTISISTLYLLFVW-LGPKWMKDREPFQMRLVLIIYNFGMVLLN----------LFIF 94

  Fly    76 K---------AYQISCIVSLPMDHKYKDRE-RLICTL--YLVNKFVDLVETIFFVLRKKDRQISF 128
            :         .|...|   ..:|:.....| |:...|  |.|:|.|:.::|:||:||||:.|:||
Mouse    95 RELFMGSYNAGYSYIC---QSVDYSNDVNEVRIAGALWWYFVSKGVEYLDTVFFILRKKNNQVSF 156

  Fly   129 LHVFHH---FAMAFFGYLYYCFHGYGGVAFPQCLLNTAVHVIMYAYYYLSSISKEVQRSLWWKKY 190
            |||:||   |.:.:.|..:..    ||.||....:|:.:|||||:||.|::....:|:.||||:|
Mouse   157 LHVYHHCTMFTLWWIGIKWVA----GGQAFFGAQMNSFIHVIMYSYYGLTAFGPWIQKYLWWKRY 217

  Fly   191 ITIAQLVQFAIILLHCTITLAQPNCAVNRPLTYGCGSLSAFFAVIFSQFYYHNYIKPGKKSAKQN 255
            :|:.|||||.:.:.|..::| ..:|...:.:.:...:.:..|..:|..||...|.:|  |.:|..
Mouse   218 LTMLQLVQFHVTIGHTALSL-YTDCPFPKWMHWALIAYAISFIFLFLNFYTRTYNEP--KQSKTG 279

  Fly   256 K 256
            |
Mouse   280 K 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eloF	NP_649956.1	ELO	11..252	CDD:279492	87/255 (34%)
Elovl4	NP_683743.2	ELO	41..277	CDD:279492	87/256 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	273..312		4/10 (40%)
		Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03204, ECO:0000269\|PubMed:24569140	308..312
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R389
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.850