DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eloF and Elovl1

DIOPT Version :9

Sequence 1:	NP_649956.1	Gene:	eloF / 41211	FlyBaseID:	FBgn0037762	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_001034265.1	Gene:	Elovl1 / 54325	MGIID:	1858959	Length:	279	Species:	Mus musculus

Alignment Length:	264	Identity:	89/264 - (33%)
Similarity:	147/264 - (55%)	Gaps:	37/264 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 PVVSNPWITMGTLIGYLLFVLKLGPKIMEHRKPFHLNGVIRIYNIFQILYNGLILVLGVHFLFV- 74
            |::.:|.:....|:.|:.|:|.|||:||.:||||.|.|       |.|:||..:::|.::.::.
Mouse    23 PLMGSPLLITSILLTYVYFILSLGPRIMANRKPFQLRG-------FMIVYNFSLVILSLYIVYEF 80

  Fly    75 -----LKAYQISCIVSLPMDHKYKDRERL----ICTLYLVNKFVDLVETIFFVLRKKDRQISFLH 130
                 |..|...|.   |:|.. ...|.|    :..|::::|.::|::|:.|:|||||.|::|||
Mouse    81 LMSGWLSTYTWRCD---PIDFS-NSPEALRMVRVAWLFMLSKVIELMDTVIFILRKKDGQVTFLH 141

  Fly   131 VFHHFAMAFFGYLYYCFHGYGGVAFPQCLLNTAVHVIMYAYYYLSSISKEVQRSLWWKKYITIAQ 195
            ||||..:. :.:.:......||:.....::|::|||:||.||.||::....|..|||||::|..|
Mouse   142 VFHHSVLP-WSWWWGIKIAPGGMGSFHAMINSSVHVVMYLYYGLSALGPVAQPYLWWKKHMTAIQ 205

  Fly   196 LVQFAIILLHCTITLAQPNCAVNRPL------TYGCGSLSAFFAVIFSQFYYHNYIKPGK---KS 251
            |:||.::.||.:.....|:|....|:      .||     ..|.::||.|:||:|.| ||   ::
Mouse   206 LIQFVLVSLHISQYYFMPSCNYQYPIIIHLIWMYG-----TIFFILFSNFWYHSYTK-GKRLPRA 264

  Fly   252 AKQN 255
            .:||
Mouse   265 VQQN 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eloF	NP_649956.1	ELO	11..252	CDD:279492	87/259 (34%)
Elovl1	NP_001034265.1	ELO	23..260	CDD:366492	86/254 (34%)
Elovl1	NP_001034265.1	Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03201	275..279
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2831
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11157
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R389
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.900