DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FBXO11 and VFB3

DIOPT Version :9

Sequence 1:	NP_001262441.1	Gene:	FBXO11 / 41209	FlyBaseID:	FBgn0037760	Length:	1182	Species:	Drosophila melanogaster
Sequence 2:	NP_567316.1	Gene:	VFB3 / 826171	AraportID:	AT4G07400	Length:	554	Species:	Arabidopsis thaliana

Alignment Length:	352	Identity:	73/352 - (20%)
Similarity:	101/352 - (28%)	Gaps:	148/352 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly   371 LPDEVLLAIFSYLMEQDLCRLALVCKRFNTIANDTELWKRLYQSVFEYDLPLFNPELCKFVFEKP 435
            ||||.|..||..|...||.|.:|||:|:.||...                       |:......
plant    77 LPDECLSLIFQSLTCADLKRCSLVCRRWLTIEGQ-----------------------CRHRLSLK 118

  Fly   436 EESEYANPWKESFRQLYRGVHVRPGYQERRSSGRSIVFFNTIQAALDYPEERAAAGV----FVPA 496
            .:|:.              :.|.|....|..|...:|.          ..:|.:.|:    ||..
plant   119 AQSDL--------------ISVIPSLFTRFDSVTKLVL----------RSDRRSLGICDNAFVMI 159

  Fly   497 GAGAGNVVSAGLSN----------------------TSASAGVGGASVNALVNI---YEEQVAPT 536
            .....|:....|..                      :..|.|.|...:|||:|.   .||
plant   160 SVRCRNLTRLKLRGCPEISDLGIIGFTENCRSLKKVSFGSCGFGVKGMNALLNTCLGLEE----- 219

  Fly   537 EHPGPLIFLHAGHYKGEYLFIDSDVALVGAAPGNVAES--VILEREAGSTVMF---VEGAKYAYV 596
                    |.....:|    |.:...|:|  ||..|.|  ||..:|..:...|   :.|||
plant   220 --------LSVKRLRG----IGAGAELIG--PGGAAGSLKVICLKELHNGQCFAPLLSGAK---- 266

  Fly   597 GYLTLKF--------------SPEVTSTVSHH--KHYCLDIG----ENCSPTVDNCIIRSTSVVG 641
            |...||.              ..:|.:.|..|  :....|:|    ..||
plant   267 GLRILKIFRCSGDWDRVFEAVRDKVNAIVEIHLERIQMSDLGLTALSKCS--------------- 316

  Fly   642 AAVCVGGVNANPVIRNCDISDCENVGL 668
                  ||....:::.   .||.||||
plant   317 ------GVEVLHLVKT---PDCTNVGL 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FBXO11	NP_001262441.1	F-box-like	370..414	CDD:289689	17/42 (40%)
		Beta_helix	650..796	CDD:289971	6/19 (32%)
		Beta_helix	735..882	CDD:289971
		Beta_helix	919..1077	CDD:289971
		ZnF_UBR1	1093..>1146	CDD:197698
VFB3	NP_567316.1	F-box-like	74..>104	CDD:289689	14/26 (54%)
		leucine-rich repeat	89..114	CDD:275381	11/47 (23%)
		leucine-rich repeat	115..165	CDD:275381	10/73 (14%)
		AMN1	<146..>226	CDD:187754	16/92 (17%)
		leucine-rich repeat	166..191	CDD:275381	1/24 (4%)
		leucine-rich repeat	192..216	CDD:275381	7/23 (30%)
		leucine-rich repeat	268..293	CDD:275381	3/24 (13%)
		leucine-rich repeat	294..317	CDD:275381	6/43 (14%)
		leucine-rich repeat	318..343	CDD:275381	7/20 (35%)
		AMN1	<340..>463	CDD:187754
		leucine-rich repeat	344..371	CDD:275381
		leucine-rich repeat	372..396	CDD:275381
		leucine-rich repeat	397..422	CDD:275381
		leucine-rich repeat	423..447	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1027299at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010