Protein Alignment FBXO11 and fbxo10

DIOPT Version :10

• Sequence 1: NP_649954.1
• Gene: FBXO11 / 41209
• FlyBaseID: FBgn0037760
• Length: 1182
• Species: Drosophila melanogaster
• Sequence 2: NP_001128729.2
• Gene: fbxo10 / 563863
• ZFINID: ZDB-GENE-090313-270
• Length: 964
• Species: Danio rerio
• Alignment Length: 1021
• Identity: 219/1021 - (21%)
• Similarity: 353/1021 - (34%)
• Gaps: 311/1021 - (30%)

  Fly   370 ELPDEVLLAIFSYLMEQDLCRLALVCKRFN--TIANDTELWKRLYQSVFEYDLPLF--NPELCKF 430
            :|..|:...|.:||...||.|..|||:.:.  .::.|:..|::|.....|...|.:  .|.|
Zfish     5 DLTVELWRLILAYLPLPDLGRCCLVCRAWRELILSLDSTRWRQLCLGCPECRHPNWPRRPHL--- 66

  Fly   431 VFEKPEESEYANPWKESFRQLYRGVHVRPGYQE-------------RRSSGRSIVFFNTIQAALD 482
                |..|     |:|:.||  ..:..|...|.             ||...|.:....|: |...
Zfish    67 ----PPAS-----WREALRQ--HALASRTWTQNGSDLHSSACLHLFRRRKDRRVWHVATV-AGGG 119

  Fly   483 YPEERAAAGVFVPAGAGAGNVVSAGLSNTSAS---------AGVGG-ASVNALVNIYEEQVAPTE 537
            |...|.|..|   ||.....|:..|:......         .|:|. ..|:.||:.  :|..||.
Zfish   120 YESLRGALAV---AGPYDKVVLHPGVYEEQVEVALKVPVEIVGMGKLGDVSLLVSF--DQQCPTA 179

  Fly   538 HPGPLIFLHA-----------GH-------YKGEYLFI--------------------------- 557
            ....::|:.|           ||       ::|..|.|
Zfish   180 RLCNVVFMPAWFSPVVYKTSSGHVQLDNCNFEGCQLHIRGPGTCQARFCSFAQGSSAHFLGVTIS 244

  Fly   558 ----------DSDVALVGAAPGN-----------VAESVILEREAGSTVMFVEGAKYA------- 594
                      ||....|...|.:           :|::..:....|||.|..:|.|.:
Zfish   245 LMDSCEFSGGDSASVTVEGPPVSERNWAFKHLVALAKTFTMMTSIGSTEMSNQGRKDSVSTGSNG 309

  Fly   595 ---YVGYLTLK--FSPEV------------------------------TST-------------- 610
               :.|..|::  ..|||                              ||:
Zfish   310 NSPFDGINTMEDWSKPEVDWETNWAKQKGGDSLLPGQDGTMIEEDSIETSSESSEEDDDDDLDGE 374

  Fly   611 ------VSHHKH-----YCLDIGENCSPTVDNC---IIRSTSVVGAAVCVGGVNANPVIRNCDIS 661
                  :|:.:|     ...|:.....||:.|.   :.:.......|..|.|.    ::|.|.:.
Zfish   375 KSTGLKLSYDQHGLAHLSMTDMPNYAFPTLLNLSAELQKDAEARDLAASVQGC----LLRRCLLR 435

  Fly   662 DCENVGLYVTDYAQGTYEHNEISRNALAGIWVKNFASPIMRENHIHHGRDVGIFTFENGMGYFEK 726
            |.:. |:::.::||...|.|.......|...::| |..:|..|.:...:..|:|...:..|...:
Zfish   436 DGKG-GVHLCNHAQARLEANMFRGLNYAVRCIQN-AKMVMLRNEVCGCKASGVFLRLSAQGLIAE 498

  Fly   727 NDIHNNRIAGFEVKAGANPTVVKCEIHHGQTGGIYVHENGLGQFIENRIHSNNFAGVWITSNSNP 791
            |:||:|..||.:::.||||.::...||.|...||.|..||.|....|:|:.|..|||:|..|.||
Zfish   499 NNIHSNGEAGLDIRKGANPIILCNRIHSGLRSGIVVLGNGRGSIRSNQIYGNKEAGVYILFNGNP 563

  Fly   792 TIRKNEIYNGHQGGVYIFGEGRGLIEHNNIYGNALAGIQIRTNSDPIVRHNKIHHGQHGGIYVHE 856
            .:..|.|:.|...|:.:...|||||..|.|..|...|..||...||::|:|.|.:|...|:.|.|
Zfish   564 VVSGNHIFQGLAAGIAVNENGRGLITENVIRQNQWGGADIRRGGDPVLRNNFICYGYSDGVVVGE 628

  Fly   857 KGQGLIEENEVYSNTLAGVWITTGSTPVLRRNRIHSGKQVGVYFY----------DNGHGKLEDN 911
            :|:||:|.|.:|.|...|||:.:.|.|.|..|.|...:..|:..:          ..|:..|:|.
Zfish   629 RGRGLVEGNHIYGNRGCGVWVMSSSLPQLIGNHISHNRMYGLAVFCRKDTESAVNREGYRALQDR 693

  Fly   912 DIFNHLYSGVQIRTGSNPVIRGNKIWGGQNGGVLVYNGGL---------------GLLEQNEIFD 961
            |                   ||.:....:.|.::.:...:               .|:|.|.|..
Zfish   694 D-------------------RGERDNFNEEGELMAWESDIDSEDERFSSRRPITVALVENNCISQ 739

  Fly   962 NAMAGVWIKTDSNPTLKRNKIYDGRDGGICIF--------------------------------- 993
            |...||::|:.....:..|.:...|..|:|:.
Zfish   740 NGAVGVFVKSSEPLNVVSNMVKSNRGAGVCVIQSAQLTRLVGNCVLCNGWTGVSVDRECRVELRG 804

  Fly   994 NG------------GKGILEENDIFRNTQAGVLISTQSHPILRRNRIYDGQAAGVEITNNATATL 1046
            ||            |.|::.|||:..||..|:.:...:...:.|||:...:..|:.:...|...:
Zfish   805 NGVYGNTCHGVCFRGDGLIVENDVVDNTTGGIRVMDNADVKVLRNRVQAVRGYGISVKQLARGVV 869

  Fly  1047 EHNQIFKNKFGGLCLASGVQPITRGNNIFNNEDEVEKAVSS-------GQCLYKISSYTSFPMHD 1104
            :.|.:::::           |.|....|..|...:|..|.:       .|.|:.:.:..:.|.:.
Zfish   870 QENLVYQSR-----------PTTTKTPIRTNAQNLECVVLNNSLLTPRSQALWALENPPARPHNS 923

  Fly  1105 FYRCQTCNT-------TDRNAICVNCIKNCHAGHDVEFIRHDRFFC 1143
            .....|.:|       |..|.|..:....||        .:...||
Zfish   924 NPSSVTPSTIPAHLALTMTNRITASVESGCH--------NNGSIFC 961

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FBXO11	NP_649954.1	F-box_FBXO11	368..412	CDD:438863	13/43 (30%)
		Beta_helix	650..798	CDD:463811	46/147 (31%)
		Beta_helix	735..890	CDD:463811	63/154 (41%)
		Beta_helix	919..1075	CDD:463811	33/215 (15%)
		UBR-box_UBR6_FBXO11	1090..1158	CDD:439074	11/61 (18%)
fbxo10	NP_001128729.2	None