DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment FBXO11 and Fbxl3

DIOPT Version :9

Sequence 1:NP_001262441.1 Gene:FBXO11 / 41209 FlyBaseID:FBgn0037760 Length:1182 Species:Drosophila melanogaster
Sequence 2:NP_001347270.1 Gene:Fbxl3 / 50789 MGIID:1354702 Length:428 Species:Mus musculus


Alignment Length:349 Identity:77/349 - (22%)
Similarity:130/349 - (37%) Gaps:72/349 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   371 LPDEVLLAIFSYLMEQDLCRLALVCKRFNTIANDTELWK----RLYQSVFEYDLPLFNPELCKFV 431
            |..:::|.:|.||...|....:.||:.:|.:.:..:||:    .|.|....| |...:|||.|.:
Mouse    39 LLQDIVLHVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSY-LKATHPELIKQI 102

  Fly   432 ------------FEKPEESEYANPWKESFRQLYR------GV--HVRPGYQERRS----SGRSIV 472
                        |:.....|.|....:...||..      |:  ..||.:.:...    |..::|
Mouse   103 IKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHFISALTVV 167

  Fly   473 FFNTIQAAL----DYPEERAAAGVFVPAGAGAGNVVSAGLSNTSASAGVGGASVNALVNIYE--E 531
            |.|:...:.    |.|.:..:..|.|     |.|..:..|...|:...|..|.:..:.:...  .
Mouse   168 FVNSKSLSSLKIDDTPVDDPSLKVLV-----ANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLR 227

  Fly   532 QVAPTEH---PGPLIFLHA-GHYKGEYLFIDSDVALVGAAPGNVAESVILEREAGSTVMFVE-GA 591
            ::|...|   ...|:.|.: .|.:.|:|.||    :|...||......|   :..|...|:: ..
Mouse   228 ELALNYHLLSDELLLALSSEKHVRLEHLRID----VVSENPGQTHFHTI---QKSSWDAFIKHSP 285

  Fly   592 KYAYVGYLTL---KFSP----EVTSTVSHHKHYCLDIGENCSPTVDNCIIRSTSVVGAAVCVGGV 649
            |...|.|..|   :|.|    |:.:|   |.::...:.::....|.....|...:|   ||..|:
Mouse   286 KVNLVMYFFLYEEEFDPFFRYEIPAT---HLYFGRSVSKDVLGRVGMTCPRLVELV---VCANGL 344

  Fly   650 NA--NPVIRNCDISDCEN---VGL 668
            ..  ..:||..:  .|:|   :||
Mouse   345 RPLDEELIRIAE--RCKNLSAIGL 366

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FBXO11NP_001262441.1 F-box-like 370..414 CDD:289689 12/46 (26%)
Beta_helix 650..796 CDD:289971 6/24 (25%)
Beta_helix 735..882 CDD:289971
Beta_helix 919..1077 CDD:289971
ZnF_UBR1 1093..>1146 CDD:197698
Fbxl3NP_001347270.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..33
F-box-like 36..77 CDD:315592 10/37 (27%)
LRR 1 119..146 5/26 (19%)
leucine-rich repeat 174..199 CDD:275381 6/29 (21%)
LRR 2 181..207 7/30 (23%)
leucine-rich repeat 200..225 CDD:275381 4/24 (17%)
LRR 3 208..233 3/24 (13%)
LRR 4 234..259 8/28 (29%)
leucine-rich repeat 252..286 CDD:275381 10/40 (25%)
leucine-rich repeat 287..333 CDD:275381 9/48 (19%)
LRR 5 316..341 4/27 (15%)
leucine-rich repeat 334..360 CDD:275381 7/30 (23%)
LRR 6 343..368 7/26 (27%)
leucine-rich repeat 361..383 CDD:275381 2/6 (33%)
LRR 7 369..394
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1027299at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.010

Return to query results.
Submit another query.