DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FBXO11 and fbxl21p

DIOPT Version :9

Sequence 1:	NP_001262441.1	Gene:	FBXO11 / 41209	FlyBaseID:	FBgn0037760	Length:	1182	Species:	Drosophila melanogaster
Sequence 2:	XP_002935952.1	Gene:	fbxl21p / 100489356	XenbaseID:	XB-GENE-987711	Length:	458	Species:	Xenopus tropicalis

Alignment Length:	367	Identity:	81/367 - (22%)
Similarity:	128/367 - (34%)	Gaps:	108/367 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   371 LPDEVLLAIFSYLMEQDLCRLALVCKRFNTIANDTELWKRLYQSVFEYD--------LPLFNPEL 427
            ||..|:|.||.||...|..|.:.||:|:|.:.:..|||::     ||::        |...:|:|
Frog    69 LPHHVVLHIFQYLPLVDRARASSVCRRWNEVFHIPELWRK-----FEFELNQPATSYLKSTHPDL 128

  Fly   428 CKFVFEK---------------PEESEYA------------------NPWKESFRQLYRGVHVRP 459
            .:.:.:|               .|.:|.|                  :..|.||..:.:...|
Frog   129 IQQIIKKHADHLQYVSFKVDSCTESAEAACDILSQLVNCSIKTLGLISTAKPSFMNVSKSHFV-- 191

  Fly   460 GYQERRSSGRSIVFFNTIQAAL----DYPEERAAAGVFVPAGAGAGNVVSAGLSNTSASAGVGGA 520
                   |..::||.|:...:.    |.|.:..:..|.|     |.|..:..|...|:...|..|
Frog   192 -------SALTVVFVNSKSLSSIKIDDTPVDDPSLKVLV-----ANNSDTLKLLKMSSCPHVSPA 244

  Fly   521 SVNALVNIYE--EQVAPTEH---PGPLIFLHA-GHYKGEYLFIDSDVALVGAAPGNVAESVILER 579
            .:..:.:...  .::|...|   ...|:.|.. .|.:.|:|.||    :|...||......|  :
Frog   245 GILCVADQCHGLRELALNYHLLSDELLLALSTEKHVRLEHLRID----VVSENPGQTQFHTI--K 303

  Fly   580 EAGSTVMFVEGAKYAYVGYLTL------KFSPEVTSTVSH-------HKHYCLDIGENCSPTVDN 631
            :.....:.....|...|.|..|      .|..|.| .|:|       .|.....||.||...::
Frog   304 KQSWDALIKHSPKVNIVMYFFLYEEEFDAFFREET-PVTHLYFGRAVSKAMLGRIGMNCPRLIE- 366

  Fly   632 CIIRSTSVVGAAVCVGGVNA--NPVIRNCDISDCEN---VGL 668
                      ..||..|:..  :.:||..|  .|:|   :||
Frog   367 ----------LVVCANGLQPLDDELIRIAD--RCKNLTAIGL 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FBXO11	NP_001262441.1	F-box-like	370..414	CDD:289689	17/42 (40%)
		Beta_helix	650..796	CDD:289971	7/24 (29%)
		Beta_helix	735..882	CDD:289971
		Beta_helix	919..1077	CDD:289971
		ZnF_UBR1	1093..>1146	CDD:197698
fbxl21p	XP_002935952.1	F-box-like	66..109	CDD:372399	17/44 (39%)
		leucine-rich repeat	204..229	CDD:275381	6/29 (21%)
		leucine-rich repeat	230..255	CDD:275381	4/24 (17%)
		leucine-rich repeat	256..281	CDD:275381	5/24 (21%)
		leucine-rich repeat	282..316	CDD:275381	8/39 (21%)
		leucine-rich repeat	327..363	CDD:275381	10/36 (28%)
		AMN1	<348..>422	CDD:187754	15/62 (24%)
		leucine-rich repeat	364..390	CDD:275381	7/38 (18%)
		leucine-rich repeat	391..416	CDD:275381	2/6 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1027299at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010