Protein Alignment CG9467 and Kctd3

DIOPT Version :10

• Sequence 1: NP_001369000.1
• Gene: CG9467 / 41207
• FlyBaseID: FBgn0037758
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_001100669.1
• Gene: Kctd3 / 305055
• RGDID: 1310658
• Length: 816
• Species: Rattus norvegicus
• Alignment Length: 717
• Identity: 387/717 - (53%)
• Similarity: 495/717 - (69%)
• Gaps: 78/717 - (10%)

  Fly     7 ASSSDLVNLNVGGQRFSTSRQTLTWIPDTFFTALLSGRISSLRDEHNAIFIDRDPTLFSIILNYL 71
            |||.::|.|||||.|||||||||.||||:||::|||||||:||||..||||||||..|:.|||:|
  Rat    14 ASSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNFL 78

  Fly    72 RTKDIDIKNCEIRALRHEAEYYGITPLTKRLALCEDLNHSSCGDLLFYGFLAAPPMPSNEAVAAT 136
            |||::|::...|..||||||:||||||.:||.|||:|..||||.:||:|:|..|.:||.:..
  Rat    79 RTKELDLRGVSINVLRHEAEFYGITPLVRRLLLCEELERSSCGSVLFHGYLPPPGIPSRKGT--- 140

  Fly   137 SVDESLPSTSASAIGSRPGSMVRVPEPSRSSHSRNSSWDLRLGRTGSTGNGANPPAPMLHSRNPS 201
                   :|:.|::.:|.|.      .|....:|.|.....|     .|||.
  Rat   141 -------NTARSSVDARNGL------SSMEGEARGSGTQPVL-----AGNGE------------- 174

  Fly   202 IDFMRHSRNSSADLNKVFRNEVGLVFSPTQNSNWVDPLRVQIIKAHQNWIAVAYAHFVTCYRVKD 266
             |.:|                :|:.         |||.:|.|:..|.|||..|||||..|||:|:
  Rat   175 -DTIR----------------LGVP---------VDPRKVLIVAGHHNWIVAAYAHFAVCYRIKE 213

  Fly   267 SNGWQQVFTSPHIDATIERIAINSKVNTSAAEPLPSKMVAISYGSQIRLWSIQEGGQKTDVGTFN 331
            |:|||||||||::|.||||:|:|:|| .........||||::..|.|.|||:|:||..:::|.|:
  Rat   214 SSGWQQVFTSPYLDWTIERVALNAKV-VGGPHGDKDKMVAVASESSIILWSVQDGGSGSEIGVFS 277

  Fly   332 LNVRVEYLFFIGSQLVALSSSGKIGVWHAMTQHWQIQDLVPVLSFDSAGSFLLLGCNNGSIYYID 396
            |.|.|:.|||||:||||.|.:||:|||:|:|||||:||:||:.|:|:||||||||||||||||||
  Rat   278 LGVPVDALFFIGNQLVATSHTGKVGVWNAVTQHWQVQDVVPITSYDTAGSFLLLGCNNGSIYYID 342

  Fly   397 MQKFPLRIKDNDLLVTELYKDVTLDPITAISVYLTPKTSSISGNWIEIAYGTKSGAVRIIVQHPE 461
            |||||||:|||||||||||.|.:.|.|||:|||||||| |:|||||||||||.|||||:||||||
  Rat   343 MQKFPLRMKDNDLLVTELYHDPSNDAITALSVYLTPKT-SVSGNWIEIAYGTSSGAVRVIVQHPE 406

  Fly   462 TAGHGPHLFETFFVHQSPVTKVMLSEKYLVSVCSEYHHVRTWRLTRFRGMLSTQPGSTPEASFKI 526
            |.|.||.||:||.||:|||||:|||||:|||||::.:|||||.:||||||:||||||||.|||||
  Rat   407 TVGSGPQLFQTFTVHRSPVTKIMLSEKHLVSVCADNNHVRTWTVTRFRGMISTQPGSTPLASFKI 471

  Fly   527 VSLEATDTSYSYAAGNDFGPYGDYDD-MIFVQKVVPETDQLYVRLASNGDRVCVIRSVDSSTISA 590
            :|||.|::..||::|||.||:|:.|| .:|:|||||.|::|:|||:|.|.|:|.|::||.:|||:
  Rat   472 LSLEETESHGSYSSGNDIGPFGERDDQQVFIQKVVPITNKLFVRLSSTGKRICEIQAVDCTTISS 536

  Fly   591 FCVLECEVSS-------RFILTGHCNGAIQMWDLTTALALLSKDEPQQKINGGPDTNELLRLLDQ 648
            |.|.|||.||       |::.|||.||:|||||||||:.:::|.|  .|..|||...|||:||||
  Rat   537 FTVRECEGSSRMGSRPRRYLFTGHTNGSIQMWDLTTAMDMVNKSE--DKDAGGPTEEELLKLLDQ 599

  Fly   649 CEISNSSCTTPCMSPCLSAMGNGSGMASSIARMKASNIALLNREPAMAMAVQAVQPPAQVQPALP 713
            |::|.|.|.||.:||..|.:.:      |..|..:|::.|.:.|.....|......|.:..|.|.
  Rat   600 CDLSTSRCATPNISPATSVLQH------SRLRESSSSLQLQHHETIHEAATYGATRPYRESPLLA 658

  Fly   714 EA 715
            .|
  Rat   659 RA 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9467	NP_001369000.1	BTB_POZ_KCTD3-like	10..95	CDD:349672	57/84 (68%)
Kctd3	NP_001100669.1	BTB_POZ_SHKBP1	17..119	CDD:349701	68/101 (67%)
		WD40	131..>450	CDD:441893	200/380 (53%)