Protein Alignment CG9467 and Shkbp1

DIOPT Version :10

• Sequence 1: NP_001369000.1
• Gene: CG9467 / 41207
• FlyBaseID: FBgn0037758
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_619617.2
• Gene: Shkbp1 / 192192
• MGIID: 2385803
• Length: 704
• Species: Mus musculus
• Alignment Length: 741
• Identity: 357/741 - (48%)
• Similarity: 476/741 - (64%)
• Gaps: 98/741 - (13%)

  Fly     5 THASSSDLVNLNVGGQRFSTSRQTLTWIPDTFFTALLSGRISSLRDEHNAIFIDRDPTLFSIILN 69
            :..:..::::|||||:||||||||||||||:||::|||||||:|:||..|||||||||:|:.|||
Mouse    13 SRGAPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILN 77

  Fly    70 YLRTKDIDIKNCEIRALRHEAEYYGITPLTKRLALCEDLNHSSCGDLLFYGFLAAPPMPSNEAVA 134
            :||||::|.:.....:|.|||::||:|||.:||.:.|:|:.||||::||.|:|..|..|......
Mouse    78 FLRTKELDPRGVHGSSLLHEAQFYGLTPLVRRLQVREELDRSSCGNVLFNGYLPPPVFPVKRRNR 142

  Fly   135 ATSVDESLPSTSASAIGSRPGSMVRVPEPSRSSHSRNSSWDLRLGRTGSTGNGANPPAPMLHSRN 199
            .:.|       ....||.||.       |.|    |:::....||..|..|.       ||..|.
Mouse   143 HSLV-------GPQQIGGRPA-------PVR----RSNTMPPNLGNAGLLGR-------MLDERA 182

  Fly   200 PSIDFMRHSRNSSADLNKVFRNEVGLVFSPTQNSNWVDPLRVQIIKAHQNWIAVAYAHFVTCYRV 264
            |                            |:.:....:|..|:::..|.|||||||.||:.|||:
Mouse   183 P----------------------------PSPSGQPEEPGMVRLVCGHHNWIAVAYTHFLVCYRL 219

  Fly   265 KDSNGWQQVFTSPHIDATIERIAINSKVNTSAAEPLPSKMVAISYGSQIRLWSIQEGGQKTDVGT 329
            |:::|||..|:||.:|..|||:|:.::| ...|.....||||.:.||:|.||::|..|..:::|.
Mouse   220 KEASGWQLAFSSPRLDWPIERLALAARV-LGGAPGEHDKMVAAATGSEILLWALQAQGGGSEIGV 283

  Fly   330 FNLNVRVEYLFFIGSQLVALSSSGKIGVWHAMTQHWQIQDLVPVLSFDSAGSFLLLGCNNGSIYY 394
            |:|.|.||.|||:|:||:|.|.:|:||||:|:|:|||:|::.|:.|:|:|||||||||:||||||
Mouse   284 FHLGVPVEALFFVGNQLIATSHTGRIGVWNAVTKHWQVQEVQPITSYDAAGSFLLLGCSNGSIYY 348

  Fly   395 IDMQKFPLRIKDNDLLVTELYKDVTLDPITAISVYLTPKTSSISGNWIEIAYGTKSGAVRIIVQH 459
            :|:||||||:|||||||:|||:|...|.:||:|||||||||. |||||||||||.||.||:||||
Mouse   349 VDVQKFPLRMKDNDLLVSELYRDPAEDGVTALSVYLTPKTSD-SGNWIEIAYGTSSGVVRVIVQH 412

  Fly   460 PETAGHGPHLFETFFVHQSPVTKVMLSEKYLVSVCSEYHHVRTWRLTRFRGMLSTQPGSTPEASF 524
            |||.|.||.||:||.||:|||||:|||||:|:|||::.:|||||.:||||||:||||||||.|||
Mouse   413 PETVGSGPQLFQTFSVHRSPVTKIMLSEKHLISVCADNNHVRTWSVTRFRGMISTQPGSTPLASF 477

  Fly   525 KIVSLEATDTSYSYAAGNDFGPYGDYDD-MIFVQKVVPETDQLYVRLASNGDRVCVIRSVDSSTI 588
            ||::||:.|.....:||||.||||:.|| .:|:|||||...||:|||:|.|.|||.:||||.|..
Mouse   478 KILALESVDGLGGCSAGNDIGPYGERDDQQVFIQKVVPNASQLFVRLSSTGQRVCSVRSVDGSPT 542

  Fly   589 SAFCVLECEVS-------SRFILTGHCNGAIQMWDLTTALALLSKDEPQQKINGGPDTNELLRLL 646
            :||.|||||.|       .|::|||..||::.|||||||:     |...|...||....||:..|
Mouse   543 TAFTVLECEGSRRLGSRPRRYLLTGQANGSLAMWDLTTAM-----DGLGQTPAGGLTEEELMDQL 602

  Fly   647 DQCEIS---NSSCTTPCMSP--CLSAMGNGSGMASSIARMKASNIALL----NREPAMAMA---- 698
            :|||:|   :|..:.|..||  .|:::.:.|           ||.:|.    :..|..|.|
Mouse   603 EQCELSPLASSRGSFPSPSPRTSLTSLHSAS-----------SNTSLYGPRGSPSPPQAEARRRG 656

  Fly   699 ----VQAVQPPAQVQPAL--PEAVAP 718
                |...|..|:..|.|  |...||
Mouse   657 AGSFVDRCQELARGAPELRWPPTPAP 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9467	NP_001369000.1	BTB_POZ_KCTD3-like	10..95	CDD:349672	54/84 (64%)
Shkbp1	NP_619617.2	BTB_POZ_SHKBP1	18..120	CDD:349701	62/101 (61%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	146..165		8/36 (22%)
		WD 1	233..280		18/47 (38%)
		WD 2	283..322		23/38 (61%)
		WD 3	324..359		25/34 (74%)
		WD 4	428..466		27/37 (73%)
		WD 5	548..586		19/42 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	609..704		20/85 (24%)
		PXXXPR. /evidence=ECO:0000305|PubMed:21830225	618..623		2/4 (50%)
		PXXXPR. /evidence=ECO:0000305|PubMed:21830225	678..683		2/5 (40%)