Protein Alignment CG8507 and C15C8.4

DIOPT Version :9

• Sequence 1: NP_649950.1
• Gene: CG8507 / 41205
• FlyBaseID: FBgn0037756
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_506187.2
• Gene: C15C8.4 / 179745
• WormBaseID: WBGene00007606
• Length: 316
• Species: Caenorhabditis elegans
• Alignment Length: 338
• Identity: 102/338 - (30%)
• Similarity: 154/338 - (45%)
• Gaps: 63/338 - (18%)

  Fly    60 FRMAKLNLVWAKAQNRLTE-PKLKSLYMELKIHDKEEIAWKQLNSQHKDKDGLK-ADELRRKLIG 122
            :|..::|.::.||...:|: ..|..|..||..:|...:|.|   |..:...|.| .|::..||..
 Worm    24 YRTERINFIYEKALQHVTDRQNLARLEKELSGYDAIYLASK---SNRQGTQGTKEIDKIDDKLGK 85

  Fly   123 IMSSYDL----------LEH---FDDTQDTEKLKPYKKFHDAEERHRNKSLFKDKKLNRLWEKAE 174
            |:..|.|          .:|   |..|.|.|.|...|              |.|:.|.:||.:|:
 Worm    86 ILEKYGLEKAVLAFKEKYKHKNLFQQTDDNEPLPSGK--------------FTDQNLQKLWSQAQ 136

  Fly   175 ISGFTAEELKSLKQEFDHHQDKVDVYYSLLENIGTVDTDKHENAINTEDLDTYNLISNDVNENDI 239
            ...|:.:||.:|..|....:.|:.||...|::...|   .|||:           |.:|:.....
 Worm   137 NGKFSQKELNALHGELKEVEQKMRVYEDQLDDFKKV---PHENS-----------IQHDIESIGD 187

  Fly   240 KTHAQNVKSFENDLNTLRGHHTGIKDHYDRLERLVSSGPHSQDFIEPKVQGLWRVAQAS-NFTVK 303
            ||  :.:|:...:||          ||.|.:.|.|:|...| .|.||:|:.||::||.: ..|..
 Worm   188 KT--KKLKAANRELN----------DHLDEVHRKVTSEEFS-PFNEPRVKRLWKLAQENEKLTPH 239

  Fly   304 ELESIKTELHHFESRLLKLRHLHAEHALQKEKYKGEKVKDKSSRFEEMEDQLK--KQTRKVEKLQ 366
            ||..:|.||.||||:|.|: ..|.|...:.::...|:.||||..:|.:|..:|  |..||..||:
 Worm   240 ELSVLKDELSHFESQLKKI-EFHKEEVSRLQEDAEERGKDKSQVYENLELSIKHEKLNRKARKLE 303

  Fly   367 ENIEKTIFKHTEL 379
            :.||:.|..|.||
 Worm   304 KYIEEKIIIHREL 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8507	NP_649950.1	Alpha-2-MRAP_N	15..140	CDD:399416	25/94 (27%)
		Alpha-2-MRAP_C	161..379	CDD:399417	72/220 (33%)
C15C8.4	NP_506187.2	Alpha-2-MRAP_C	123..310	CDD:368884	70/214 (33%)
		RAP	218..316	CDD:384230	39/98 (40%)
		3-helical coiled coil	223..230	CDD:269812	3/6 (50%)
		3-helical coiled coil	240..261	CDD:269812	11/21 (52%)
		3-helical coiled coil	294..309	CDD:269812	7/14 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166716
Domainoid	1	1.000	97	1.000	Domainoid score	I4567
eggNOG	1	0.900	-	-		E1_KOG3956
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3488
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49282
OrthoDB	1	1.010	-	-		D388256at33208
OrthoFinder	1	1.000	-	-		FOG0007150
OrthoInspector	1	1.000	-	-		oto17573
orthoMCL	1	0.900	-	-		OOG6_107561
Panther	1	1.100	-	-	LDO	PTHR16560
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6462
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.840