DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8500 and Diras2

DIOPT Version :9

Sequence 1:	NP_001303452.1	Gene:	CG8500 / 41203	FlyBaseID:	FBgn0037754	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	NP_001019645.1	Gene:	Diras2 / 68203	MGIID:	1915453	Length:	199	Species:	Mus musculus

Alignment Length:	194	Identity:	149/194 - (76%)
Similarity:	171/194 - (88%)	Gaps:	2/194 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PEQSNDYRVVVFGAGGVGKSSLVLRFIKGTFRESYIPTIEDTYRQVISCNKNICTLQITDTTGSH 77
            |||||||||.||||||||||||||||:|||||||||||:||||||||||:|:|||||||||||||
Mouse     2 PEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSH 66

  Fly    78 QFPAMQRLSISKGHAFILVYSVCSKQSLEELRPIWALIKELKGADIPNIPVMLVGNKCDETAELR 142
            |||||||||||||||||||||:.|:||||||:||:..|.|:|| |:.:||:|||||||||:.. |
Mouse    67 QFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKG-DVESIPIMLVGNKCDESPN-R 129

  Fly   143 EVSQAEGQAQATTWSISFMETSAKTNHNVTELFQELLNMEKTRTVSLQLDTKKQKKQKKEKKSK 206
            ||..:|.:|.|.||..:|||||||.||||.||||||||:||.||||||:|.||.|:||:::|.|
Mouse   130 EVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLK 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8500	NP_001303452.1	ARHI_like	18..183	CDD:206711	128/164 (78%)
Diras2	NP_001019645.1	ARHI_like	7..170	CDD:206711	128/164 (78%)
Diras2	NP_001019645.1	Effector region. /evidence=ECO:0000255	36..44		6/7 (86%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833455
Domainoid	1	1.000	250	1.000	Domainoid score	I2101
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56777
Inparanoid	1	1.050	299	1.000	Inparanoid score	I2685
Isobase	1	0.950	-	0	Normalized mean entropy	S634
OMA	1	1.010	-	-		QHG48239
OrthoDB	1	1.010	-	-		D1218505at2759
OrthoFinder	1	1.000	-	-		FOG0002912
OrthoInspector	1	1.000	-	-		otm43995
orthoMCL	1	0.900	-	-		OOG6_106316
Panther	1	1.100	-	-	LDO	PTHR24070
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5443
SonicParanoid	1	1.000	-	-		X1920
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750