Protein Alignment CG8500 and RHEB

DIOPT Version :10

• Sequence 1: NP_649948.1
• Gene: CG8500 / 41203
• FlyBaseID: FBgn0037754
• Length: 233
• Species: Drosophila melanogaster
• Sequence 2: NP_005605.1
• Gene: RHEB / 6009
• HGNCID: 10011
• Length: 184
• Species: Homo sapiens
• Alignment Length: 222
• Identity: 73/222 - (32%)
• Similarity: 114/222 - (51%)
• Gaps: 43/222 - (19%)

  Fly    15 QSNDYRVVVFGAGGVGKSSLVLRFIKGTFRESYIPTIEDTYRQVISCNKNICTLQITDTTGSHQ- 78
            ||...::.:.|...||||||.::|::|.|.:||.||||:|:.::|:.|.....||:.||.|..:
Human     3 QSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67

  Fly    79 --FPAMQRLSISKGHAFILVYSVCSKQSLEELRPIWALIKELKGADIPNIPVMLVGNKCDETAEL 141
              ||....:.|   :.:||||||.|.:|.|.::.|...:.::.|.  ..||:||||||.|...|
Human    68 SIFPQTYSIDI---NGYILVYSVTSIKSFEVIKVIHGKLLDMVGK--VQIPIMLVGNKKDLHME- 126

  Fly   142 REVSQAEGQAQATTWSISFMETSAKTNHNVTELFQELLNMEKTRTVSLQLDTKKQKKQKKEKKSK 206
            |.:|..||:|.|.:|:.:|:|:|||.|....::|:.::           |:.:|..
Human   127 RVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRII-----------LEAEKMD--------- 171

  Fly   207 DTNGSIPENGDAGASASGGAKEKCRVM 233
                        ||::.|  |..|.||
Human   172 ------------GAASQG--KSSCSVM 184

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8500	NP_649948.1	ARHI_like	18..183	CDD:206711	62/167 (37%)
RHEB	NP_005605.1	RheB	6..184	CDD:206709	69/217 (32%)
		Effector region. /evidence=ECO:0000305	35..43		5/7 (71%)