DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8500 and diras1b

DIOPT Version :9

Sequence 1:	NP_001303452.1	Gene:	CG8500 / 41203	FlyBaseID:	FBgn0037754	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	NP_001119893.1	Gene:	diras1b / 565395	ZFINID:	ZDB-GENE-070912-620	Length:	198	Species:	Danio rerio

Alignment Length:	221	Identity:	148/221 - (66%)
Similarity:	172/221 - (77%)	Gaps:	24/221 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PEQSNDYRVVVFGAGGVGKSSLVLRFIKGTFRESYIPTIEDTYRQVISCNKNICTLQITDTTGSH 77
            ||||||||||||||||||||||||||:|||||::||||:||||||||||:|::||||||||||||
Zfish     2 PEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTVEDTYRQVISCDKSVCTLQITDTTGSH 66

  Fly    78 QFPAMQRLSISKGHAFILVYSVCSKQSLEELRPIWALIKELKGADIPNIPVMLVGNKCDETAELR 142
            |||||||||||||||||||||:.||||||||:||:..|..:|| ::.|||:||||||.|||.  |
Zfish    67 QFPAMQRLSISKGHAFILVYSITSKQSLEELKPIYQQILAIKG-NVENIPIMLVGNKSDETQ--R 128

  Fly   143 EVSQAEGQAQATTWSISFMETSAKTNHNVTELFQELLNMEKTRTVSLQLDTKKQKKQKKEKKSKD 207
            ||...:|:||:.||..:|||||||||||||||||||||:||.|::||.:|.|:..||.:..|
Zfish   129 EVKTEDGEAQSKTWKCAFMETSAKTNHNVTELFQELLNLEKKRSMSLNIDGKRSGKQSRADK--- 190

  Fly   208 TNGSIPENGDAGASASGGAKEKCRVM 233
                              .|.||.||
Zfish   191 ------------------LKGKCSVM 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8500	NP_001303452.1	ARHI_like	18..183	CDD:206711	128/164 (78%)
diras1b	NP_001119893.1	P-loop_NTPase	7..169	CDD:304359	128/164 (78%)
diras1b	NP_001119893.1	small_GTPase	17..171	CDD:197466	120/156 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	253	1.000	Domainoid score	I2029
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	290	1.000	Inparanoid score	I2785
OMA	1	1.010	-	-		QHG48239
OrthoDB	1	1.010	-	-		D1218505at2759
OrthoFinder	1	1.000	-	-		FOG0002912
OrthoInspector	1	1.000	-	-		otm25076
orthoMCL	1	0.900	-	-		OOG6_106316
Panther	1	1.100	-	-	LDO	PTHR24070
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5443
SonicParanoid	1	1.000	-	-		X1920
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	12.010