Protein Alignment CG8500 and KRAS

DIOPT Version :10

• Sequence 1: NP_649948.1
• Gene: CG8500 / 41203
• FlyBaseID: FBgn0037754
• Length: 233
• Species: Drosophila melanogaster
• Sequence 2: XP_047284782.1
• Gene: KRAS / 3845
• HGNCID: 6407
• Length: 227
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 77/242 - (31%)
• Similarity: 122/242 - (50%)
• Gaps: 43/242 - (17%)

  Fly    18 DYRVVVFGAGGVGKSSLVLRFIKGTFRESYIPTIEDTYRQVISCNKNICTLQITDTTGSHQFPAM 82
            :|::||.||||||||:|.::.|:..|.:.|.|||||:||:.:..:...|.|.|.||.|..::.||
Human     3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAM 67

  Fly    83 QRLSISKGHAFILVYSVCSKQSLEELRPIWALIKELKGADIPNIPVMLVGNKCDETAELREVSQA 147
            :...:..|..|:.|:::.:.:|.|::......||.:|  |..::|::|||||||..:  |.|...
Human    68 RDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVK--DSEDVPMVLVGNKCDLPS--RTVDTK 128

  Fly   148 EGQAQATTWSISFMETSAKTNHNVTELFQELLNMEKTRTVSLQLDTKKQK--------------- 197
            :.|..|.::.|.|:||||||...|.:.|..|  :.:.|...|:..:|::|
Human   129 QAQDLARSYGIPFIETSAKTRQRVEDAFYTL--VREIRQYRLKKISKEEKTPGCVKIKKCIIMGV 191

  Fly   198 -----------KQKKEKKSKDTNGSIPENGDAGASASGGAKEKCRVM 233
                       ::.|||.|||           |......:|.||.:|
Human   192 DDAFYTLVREIRKHKEKMSKD-----------GKKKKKKSKTKCVIM 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8500	NP_649948.1	ARHI_like	18..183	CDD:206711	62/164 (38%)
KRAS	XP_047284782.1	H_N_K_Ras_like	3..164	CDD:133338	62/166 (37%)