DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8500 and diras1a

DIOPT Version :9

Sequence 1:	NP_001303452.1	Gene:	CG8500 / 41203	FlyBaseID:	FBgn0037754	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	NP_956125.1	Gene:	diras1a / 327577	ZFINID:	ZDB-GENE-030131-5788	Length:	195	Species:	Danio rerio

Alignment Length:	221	Identity:	141/221 - (63%)
Similarity:	168/221 - (76%)	Gaps:	27/221 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PEQSNDYRVVVFGAGGVGKSSLVLRFIKGTFRESYIPTIEDTYRQVISCNKNICTLQITDTTGSH 77
            ||||||||||||||||||||||||||:|||||::||||:||||||||||:|::|||:||||||||
Zfish     2 PEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTVEDTYRQVISCDKSVCTLEITDTTGSH 66

  Fly    78 QFPAMQRLSISKGHAFILVYSVCSKQSLEELRPIWALIKELKGADIPNIPVMLVGNKCDETAELR 142
            |||||||||||||:|||||||:.|:||||||:||:..:..:|| ::.|||:||||||.|||.  |
Zfish    67 QFPAMQRLSISKGYAFILVYSITSRQSLEELKPIYQQVLAIKG-NVENIPIMLVGNKSDETQ--R 128

  Fly   143 EVSQAEGQAQATTWSISFMETSAKTNHNVTELFQELLNMEKTRTVSLQLDTKKQKKQKKEKKSKD 207
            ||...||:|||.||..:|||||||||.||.||||||||::|.|.:||.:.:.||::..|
Zfish   129 EVETKEGEAQANTWKCAFMETSAKTNTNVKELFQELLNLDKKRDMSLNMRSSKQRRADK------ 187

  Fly   208 TNGSIPENGDAGASASGGAKEKCRVM 233
                              .|.||.||
Zfish   188 ------------------LKAKCSVM 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8500	NP_001303452.1	ARHI_like	18..183	CDD:206711	124/164 (76%)
diras1a	NP_956125.1	P-loop_NTPase	7..169	CDD:304359	124/164 (76%)
diras1a	NP_956125.1	RAS	20..171	CDD:214541	112/153 (73%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	253	1.000	Domainoid score	I2029
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	290	1.000	Inparanoid score	I2785
OMA	1	1.010	-	-		QHG48239
OrthoDB	1	1.010	-	-		D1218505at2759
OrthoFinder	1	1.000	-	-		FOG0002912
OrthoInspector	1	1.000	-	-		otm25076
orthoMCL	1	0.900	-	-		OOG6_106316
Panther	1	1.100	-	-	O	PTHR24070
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1920
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.840