DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8500 and drn-1

DIOPT Version :9

Sequence 1:	NP_001303452.1	Gene:	CG8500 / 41203	FlyBaseID:	FBgn0037754	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	NP_001333544.2	Gene:	drn-1 / 183765	WormBaseID:	WBGene00016911	Length:	219	Species:	Caenorhabditis elegans

Alignment Length:	195	Identity:	124/195 - (63%)
Similarity:	150/195 - (76%)	Gaps:	2/195 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 TRAAPEQSNDYRVVVFGAGGVGKSSLVLRFIKGTFRESYIPTIEDTYRQVISCN-KNICTLQITD 72
            ::.|...::||||.|||||||||||:..||:||||.|:|:|||||||||||||| ||:|||||||
Worm    21 SKVAEASTSDYRVAVFGAGGVGKSSITQRFVKGTFNENYVPTIEDTYRQVISCNQKNVCTLQITD 85

  Fly    73 TTGSHQFPAMQRLSISKGHAFILVYSVCSKQSLEELRPIWALIKELKGADIPNIPVMLVGNKCDE 137
            ||||||||||||||||||:||||:|||.:|||..||.||..::||:||..|...|:||||||.||
Worm    86 TTGSHQFPAMQRLSISKGNAFILIYSVTNKQSFAELVPIIEMMKEVKGNAIAETPIMLVGNKKDE 150

  Fly   138 TAELREVSQAEGQAQATTWSISFMETSAKTNHNVTELFQELLNMEKTRTVSLQLDTKKQKKQKKE 202
            .:: ||||...||..||.....|:|||||.|.|:|||||:||.:||.|.::|.:|....|..||:
Worm   151 ESK-REVSSNSGQKVATNMECGFIETSAKNNENITELFQQLLALEKKRQLALTMDDPDGKNGKKK 214

Fly 203 202
Worm 215 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8500	NP_001303452.1	ARHI_like	18..183	CDD:206711	115/165 (70%)
drn-1	NP_001333544.2	P-loop_NTPase	30..195	CDD:328724	115/165 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	218	1.000	Domainoid score	I1537
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	240	1.000	Inparanoid score	I2102
Isobase	1	0.950	-	0	Normalized mean entropy	S634
OMA	1	1.010	-	-		QHG48239
OrthoDB	1	1.010	-	-		D1218505at2759
OrthoFinder	1	1.000	-	-		FOG0002912
OrthoInspector	1	1.000	-	-		oto20820
orthoMCL	1	0.900	-	-		OOG6_106316
Panther	1	1.100	-	-	LDO	PTHR24070
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5443
SonicParanoid	1	1.000	-	-		X1920
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.860