| Sequence 1: | NP_649945.1 | Gene: | topi / 41199 | FlyBaseID: | FBgn0037751 | Length: | 814 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_003416.1 | Gene: | ZNF45 / 7596 | HGNCID: | 13111 | Length: | 682 | Species: | Homo sapiens |
| Alignment Length: | 753 | Identity: | 188/753 - (24%) |
|---|---|---|---|
| Similarity: | 275/753 - (36%) | Gaps: | 209/753 - (27%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 16 VELDQQLTPD--------------------DLQPGATVLATNESTG--GLERIVSHEEL--SRFF 56
Fly 57 AVGPAGALPMPTDVV-VERTLADPAFKQILQEADGKKGFDPQAEQMKIRDFLAGVTSSKMTTEQS 120
Fly 121 VFHG-----SRSNSSASTVNR--------IKCPTC---LVQFDAV-AFQNHSCEAK--------- 159
Fly 160 --------PIEVAVPQQEKPHL-------VPTVSAPPAPLSKPASERVIRENQVRL----RRYIK 205
Fly 206 DEMKYDLATGIESSRKNAAKGPNECTMCDRKFVHASGLVRHMEKHALDLIPSQTSEQPHTIPAAG 270
Fly 271 LHVVVKCNSCGRIF-YDPQVAFRHGLIHDSEHSTMRQSPMTQVPSNRADFNELLLDGEMLIDNDP 334
Fly 335 AFATSNQNTNPPKKEMFSSLILGSVLQCEFCEYIFADIAELLVHSASHVAERRFECTACDIQMNT 399
Fly 400 AKEASIHFQTDCIFMREAIRSLNVTLSRYFVCNVCELKFANTDLLQEHRCTSFHYFPRLNENGKK 464
Fly 465 LLLP--CDFCDVNFEFAHDFLAHSEEKHLNKKKREKETRNTGAGRIRQYLCDICGKSYTQSSHLW 527
Fly 528 QHLRFHQGVKPFVCQEENCDRKFTIRPDLNDHIRKCHTGERPYLCLVCGKRFLTGSVFYQHRLIH 592
Fly 593 RGERRYECEECGKRFYRADALKNHQRIHTGEKPYSCLFCTKTFRQRGDRDKHIRARHSHLDANSR 657
Fly 658 LMMQMQKFQLETAAAQKAQS---------HNPEQQDND 686 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| topi | NP_649945.1 | C2H2 Zn finger | 230..250 | CDD:275368 | 6/19 (32%) |
| C2H2 Zn finger | 277..297 | CDD:275368 | 7/20 (35%) | ||
| C2H2 Zn finger | 431..453 | CDD:275368 | 5/21 (24%) | ||
| COG5048 | <450..647 | CDD:227381 | 70/198 (35%) | ||
| C2H2 Zn finger | 469..490 | CDD:275368 | 5/20 (25%) | ||
| zf-C2H2 | 511..533 | CDD:278523 | 10/21 (48%) | ||
| C2H2 Zn finger | 513..564 | CDD:275368 | 19/50 (38%) | ||
| C2H2 Zn finger | 541..561 | CDD:275368 | 6/19 (32%) | ||
| zf-H2C2_2 | 555..581 | CDD:290200 | 14/25 (56%) | ||
| C2H2 Zn finger | 572..592 | CDD:275368 | 9/19 (47%) | ||
| zf-H2C2_2 | 585..609 | CDD:290200 | 13/23 (57%) | ||
| zf-C2H2 | 598..620 | CDD:278523 | 11/21 (52%) | ||
| C2H2 Zn finger | 600..620 | CDD:275368 | 10/19 (53%) | ||
| zf-H2C2_2 | 612..637 | CDD:290200 | 14/24 (58%) | ||
| C2H2 Zn finger | 628..646 | CDD:275368 | 4/17 (24%) | ||
| ZNF45 | NP_003416.1 | KRAB | 8..67 | CDD:214630 | 5/21 (24%) |
| KRAB | 8..47 | CDD:279668 | 1/1 (100%) | ||
| C2H2 Zn finger | 166..186 | CDD:275368 | 6/19 (32%) | ||
| COG5048 | 190..602 | CDD:227381 | 132/515 (26%) | ||
| C2H2 Zn finger | 194..214 | CDD:275368 | 5/19 (26%) | ||
| C2H2 Zn finger | 251..270 | CDD:275368 | 5/18 (28%) | ||
| C2H2 Zn finger | 278..298 | CDD:275368 | 3/21 (14%) | ||
| zf-H2C2_2 | 290..314 | CDD:290200 | 8/34 (24%) | ||
| C2H2 Zn finger | 306..326 | CDD:275368 | 6/19 (32%) | ||
| zf-H2C2_2 | 319..343 | CDD:290200 | 12/42 (29%) | ||
| C2H2 Zn finger | 334..354 | CDD:275368 | 7/20 (35%) | ||
| zf-H2C2_2 | 346..370 | CDD:290200 | 5/35 (14%) | ||
| C2H2 Zn finger | 362..382 | CDD:275368 | 3/23 (13%) | ||
| zf-H2C2_2 | 374..397 | CDD:290200 | 8/40 (20%) | ||
| C2H2 Zn finger | 390..410 | CDD:275368 | 7/19 (37%) | ||
| zf-H2C2_2 | 402..427 | CDD:290200 | 8/24 (33%) | ||
| C2H2 Zn finger | 418..438 | CDD:275368 | 6/19 (32%) | ||
| zf-H2C2_2 | 430..455 | CDD:290200 | 7/37 (19%) | ||
| C2H2 Zn finger | 446..466 | CDD:275368 | 5/28 (18%) | ||
| zf-H2C2_2 | 458..483 | CDD:290200 | 8/36 (22%) | ||
| C2H2 Zn finger | 474..494 | CDD:275368 | 5/32 (16%) | ||
| zf-H2C2_2 | 486..511 | CDD:290200 | 9/40 (23%) | ||
| C2H2 Zn finger | 502..522 | CDD:275368 | 9/19 (47%) | ||
| zf-H2C2_2 | 514..538 | CDD:290200 | 10/25 (40%) | ||
| C2H2 Zn finger | 530..550 | CDD:275368 | 6/22 (27%) | ||
| zf-H2C2_2 | 543..565 | CDD:290200 | 13/22 (59%) | ||
| C2H2 Zn finger | 558..578 | CDD:275368 | 9/19 (47%) | ||
| zf-H2C2_2 | 570..595 | CDD:290200 | 13/24 (54%) | ||
| zf-C2H2 | 584..606 | CDD:278523 | 11/21 (52%) | ||
| C2H2 Zn finger | 586..606 | CDD:275368 | 10/19 (53%) | ||
| zf-H2C2_2 | 598..622 | CDD:290200 | 14/34 (41%) | ||
| C2H2 Zn finger | 614..634 | CDD:275368 | 8/30 (27%) | ||
| zf-H2C2_2 | 626..650 | CDD:290200 | 4/23 (17%) | ||
| C2H2 Zn finger | 642..662 | CDD:275368 | 2/19 (11%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 662..682 | 3/9 (33%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||