DRSC/TRiP Functional Genomics Resources

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Protein Alignment topi and Zfp524

DIOPT Version :9

Sequence 1:NP_649945.1 Gene:topi / 41199 FlyBaseID:FBgn0037751 Length:814 Species:Drosophila melanogaster
Sequence 2:NP_079600.1 Gene:Zfp524 / 66056 MGIID:1916740 Length:321 Species:Mus musculus


Alignment Length:250 Identity:60/250 - (24%)
Similarity:88/250 - (35%) Gaps:77/250 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   504 GAGRIR-QYLCDICGKSYTQSSHLWQHLRFHQGVKPFVCQEENCDRKFTIRPDLNDHIRKCHTGE 567
            |:|..| .:.|.:|.:::...|.|.:|...|..:||.||::                        
Mouse   101 GSGSKRAPHFCPVCLRAFPYLSDLERHSISHSELKPHVCKD------------------------ 141

  Fly   568 RPYLCLVCGKRFLTGSVFYQHRLIHRGERRYECEECGKRFYRADALKNHQRIHTGEKPYSCLFCT 632
                   |||.|...|...:|..||.|.|.:.|..|.:||..|..|.:|.|||:||:||.|..|.
Mouse   142 -------CGKTFKRSSHLRRHCNIHAGLRPFRCVLCPRRFREAGELAHHHRIHSGERPYQCPSCR 199

  Fly   633 KTFRQRGDRDKHIRARHSHL------------------DANSRLMMQ--MQKFQLE--------- 668
            ..|.:.....:|.:.:|..|                  |.:..:.:|  :|:...|         
Mouse   200 VRFTEANTLRRHYKRKHPELVGMPVRLCPPNPRTQPLWDDDEGIPVQEGVQEESPEGKEPTWPIS 264

  Fly   669 ---------TAAAQKAQSHNPEQQDNDVAGGASTSD-------VPSGSGFMSTEP 707
                     ||..........|.||..|:||..|.:       .|.|.|.:...|
Mouse   265 STTSPLSGFTAGGSAGAGRGQEGQDTLVSGGIPTMEGDQKQGPKPLGPGAIGHPP 319

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
topiNP_649945.1 C2H2 Zn finger 230..250 CDD:275368
C2H2 Zn finger 277..297 CDD:275368
C2H2 Zn finger 431..453 CDD:275368
COG5048 <450..647 CDD:227381 41/143 (29%)
C2H2 Zn finger 469..490 CDD:275368
zf-C2H2 511..533 CDD:278523 5/21 (24%)
C2H2 Zn finger 513..564 CDD:275368 10/50 (20%)
C2H2 Zn finger 541..561 CDD:275368 1/19 (5%)
zf-H2C2_2 555..581 CDD:290200 4/25 (16%)
C2H2 Zn finger 572..592 CDD:275368 6/19 (32%)
zf-H2C2_2 585..609 CDD:290200 9/23 (39%)
zf-C2H2 598..620 CDD:278523 8/21 (38%)
C2H2 Zn finger 600..620 CDD:275368 8/19 (42%)
zf-H2C2_2 612..637 CDD:290200 12/24 (50%)
C2H2 Zn finger 628..646 CDD:275368 4/17 (24%)
Zfp524NP_079600.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..80
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 86..105 2/3 (67%)
COG5048 <102..218 CDD:227381 41/146 (28%)
C2H2 Zn finger 111..131 CDD:275368 5/19 (26%)
C2H2 Zn finger 139..159 CDD:275368 7/50 (14%)
C2H2 Zn finger 167..187 CDD:275368 8/19 (42%)
C2H2 Zn finger 195..216 CDD:275368 4/20 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 248..321 14/71 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24390
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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