Protein Alignment topi and vezf1b

DIOPT Version :9

• Sequence 1: NP_649945.1
• Gene: topi / 41199
• FlyBaseID: FBgn0037751
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: NP_001073432.1
• Gene: vezf1b / 556915
• ZFINID: ZDB-GENE-060825-121
• Length: 460
• Species: Danio rerio
• Alignment Length: 446
• Identity: 87/446 - (19%)
• Similarity: 138/446 - (30%)
• Gaps: 160/446 - (35%)

  Fly   160 PIEVAVPQQEKPHL-VPTVSAPPAPLSKPASERVIRENQVRLRRYIKDEMKYDLATG-------- 215
            |:..:.||.:||.| :|....||          :|..:      .:||.|......|
Zfish    30 PLLNSEPQDQKPVLPIPLDQKPP----------IISSD------LLKDNMGGGTGGGGGGGGGGP 78

  Fly   216 IESSRKNAAKGPNECTMCDRKFVHASGLVRHMEKH-ALDLI--PSQTSEQPHTIPAAGLHVVVKC 277
            :...::..:|.|..|:.|.:.|..:..|.||...| .:.::  |.:|:..|..:|.  :..|.:.
Zfish    79 VVIKKEPKSKTPFICSYCSKAFRDSYHLRRHESCHTGIKMVSRPKKTTTAPTMVPL--ISTVPRD 141

  Fly   278 NSCGRIFYDPQVAFRHGLIHDSEHSTMRQSPMTQVPSNRADFNELLLDGEMLIDNDPAFATSNQN 342
            |: |...|...||   |::          :..|...|..|....:|...:..:...|
Zfish   142 NN-GNPSYVSTVA---GIL----------TTATTSASTAAGIMSVLPQQQPTVPKKP-------- 184

  Fly   343 TNPPKKEMFSSLILGSVLQCEFCEYIFADIAELLVHSASHVAERRFECTACDIQMNTAKEASIHF 407
            ..|.||..          .||.|...|.|:..|..|..||..|:.|||.
Zfish   185 PKPVKKNH----------GCEMCGKAFRDVYHLNRHKLSHSDEKPFECP---------------- 223

  Fly   408 QTDCIFMREAIRSLNVTLSRYFVCNVCELKFANTDLLQEHRCTSFHYFPRLNENGKKLLLPCDFC 472
                                     :|..:|...|.:..|
Zfish   224 -------------------------ICHQRFKRKDRMTYH------------------------- 238

  Fly   473 DVNFEFAHDFLAHSEEKHLNKKKREKETRNTGAGRIRQYLCDICGKSYTQSSHLWQHLR-FHQGV 536
                                       .|:...|..:.|:|.:|||.:::..||..|:: .|...
Zfish   239 ---------------------------VRSHDGGVHKPYICSVCGKGFSRPDHLSCHVKHVHSTE 276

  Fly   537 KPFVCQEENCDRKFTIRPDLNDHIRKCHTGERPYLCLVCGKRFLTGSVFYQHRLIH 592
            :||.||...|...|..:..|..|:.: |.|:  ..|.:||| .|:.:....|...|
Zfish   277 RPFKCQVTACTSAFATKDRLRSHMIR-HEGK--VTCNICGK-MLSAAYITSHLKTH 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
topi	NP_649945.1	C2H2 Zn finger	230..250	CDD:275368	6/19 (32%)
		C2H2 Zn finger	277..297	CDD:275368	6/19 (32%)
		C2H2 Zn finger	431..453	CDD:275368	4/21 (19%)
		COG5048	<450..647	CDD:227381	28/144 (19%)
		C2H2 Zn finger	469..490	CDD:275368	0/20 (0%)
		zf-C2H2	511..533	CDD:278523	8/22 (36%)
		C2H2 Zn finger	513..564	CDD:275368	16/51 (31%)
		C2H2 Zn finger	541..561	CDD:275368	6/19 (32%)
		zf-H2C2_2	555..581	CDD:290200	8/25 (32%)
		C2H2 Zn finger	572..592	CDD:275368	6/19 (32%)
		zf-H2C2_2	585..609	CDD:290200	2/8 (25%)
		zf-C2H2	598..620	CDD:278523
		C2H2 Zn finger	600..620	CDD:275368
		zf-H2C2_2	612..637	CDD:290200
		C2H2 Zn finger	628..646	CDD:275368
vezf1b	NP_001073432.1	C2H2 Zn finger	93..113	CDD:275368	6/19 (32%)
		C2H2 Zn finger	194..214	CDD:275368	7/19 (37%)
		zf-H2C2_2	206..231	CDD:290200	10/65 (15%)
		C2H2 Zn finger	222..242	CDD:275368	6/112 (5%)
		C2H2 Zn finger	252..270	CDD:275368	7/17 (41%)
		C2H2 Zn finger	281..303	CDD:275368	6/22 (27%)
		C2H2 Zn finger	309..328	CDD:275368	6/19 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100