DRSC/TRiP Functional Genomics Resources

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Protein Alignment topi and CG17385

DIOPT Version :9

Sequence 1:NP_649945.1 Gene:topi / 41199 FlyBaseID:FBgn0037751 Length:814 Species:Drosophila melanogaster
Sequence 2:NP_001286418.1 Gene:CG17385 / 36603 FlyBaseID:FBgn0033934 Length:278 Species:Drosophila melanogaster


Alignment Length:262 Identity:74/262 - (28%)
Similarity:106/262 - (40%) Gaps:65/262 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   469 CDFCDVNFEFAHDFLAHSEEKHLNKKKREKETRNTGAGRIRQYLCDICGKSYTQSSHLWQHLRFH 533
            |..||..|....|...|.:|.|.:.|              ..|.|.:|.||:..|.:|.:|::.|
  Fly    18 CKRCDRTFRSKRDQTLHRQEVHNHNK--------------TTYECKLCAKSFCNSGNLDRHMKVH 68

  Fly   534 QGVKPFVCQEENCDRKFTIRPDLNDHIRKCHTGERPYLCLVCGKRFLTGSVFYQHRLIHRGERRY 598
            ..|:||||  ..|.:.|....:|..|. ..|:||||:.|..|.|.|...|...:|::.|.||:.:
  Fly    69 NDVRPFVC--NICSKAFAQAVNLQRHY-AVHSGERPFTCNFCNKSFTQQSNMKRHKMTHTGEKPF 130

  Fly   599 ECEECGKRFYRADALKNHQRIHTGEKPYSCLFCTKTFRQRGDRDKHIRARHSHLDANSRLMMQMQ 663
            .|:.||:.|.:...||.|:..|...|||.|.:|.|.|.|..:..:|:                  
  Fly   131 RCQRCGRYFSQLVNLKKHKLGHLNAKPYQCNYCEKGFTQLSNFKRHL------------------ 177

  Fly   664 KFQLETAAAQKAQSHNPEQQDNDVAGGASTSDVPSGSGFMSTEPSVAEMQYSITPEQQ----EEM 724
                        |||..|..|         .|||:     |.:.:.|..:..:..||:    |.|
  Fly   178 ------------QSHIKEGVD---------VDVPA-----SIQAAAALARERLESEQKPSFFECM 216

  Fly   725 VC 726
            ||
  Fly   217 VC 218

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
topiNP_649945.1 C2H2 Zn finger 230..250 CDD:275368
C2H2 Zn finger 277..297 CDD:275368
C2H2 Zn finger 431..453 CDD:275368
COG5048 <450..647 CDD:227381 58/177 (33%)
C2H2 Zn finger 469..490 CDD:275368 7/20 (35%)
zf-C2H2 511..533 CDD:278523 8/21 (38%)
C2H2 Zn finger 513..564 CDD:275368 17/50 (34%)
C2H2 Zn finger 541..561 CDD:275368 5/19 (26%)
zf-H2C2_2 555..581 CDD:290200 11/25 (44%)
C2H2 Zn finger 572..592 CDD:275368 6/19 (32%)
zf-H2C2_2 585..609 CDD:290200 8/23 (35%)
zf-C2H2 598..620 CDD:278523 7/21 (33%)
C2H2 Zn finger 600..620 CDD:275368 7/19 (37%)
zf-H2C2_2 612..637 CDD:290200 11/24 (46%)
C2H2 Zn finger 628..646 CDD:275368 6/17 (35%)
CG17385NP_001286418.1 COG5048 <13..181 CDD:227381 60/209 (29%)
C2H2 Zn finger 18..39 CDD:275368 7/20 (35%)
C2H2 Zn finger 48..68 CDD:275368 7/19 (37%)
C2H2 Zn finger 76..96 CDD:275368 5/22 (23%)
C2H2 Zn finger 104..124 CDD:275368 6/19 (32%)
C2H2 Zn finger 132..148 CDD:275368 6/15 (40%)
C2H2 Zn finger 160..180 CDD:275368 7/49 (14%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45446656
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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