DRSC/TRiP Functional Genomics Resources

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Protein Alignment topi and Zfp524

DIOPT Version :9

Sequence 1:NP_649945.1 Gene:topi / 41199 FlyBaseID:FBgn0037751 Length:814 Species:Drosophila melanogaster
Sequence 2:NP_001102375.1 Gene:Zfp524 / 365179 RGDID:1565485 Length:314 Species:Rattus norvegicus


Alignment Length:242 Identity:59/242 - (24%)
Similarity:87/242 - (35%) Gaps:74/242 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   504 GAGRIR-QYLCDICGKSYTQSSHLWQHLRFHQGVKPFVCQEENCDRKFTIRPDLNDHIRKCHTGE 567
            |:|..| .:.|.:|.:::...|.|.:|...|..:||.||::                        
  Rat   101 GSGSKRAPHFCPVCLRAFPYLSDLERHSISHSELKPHVCKD------------------------ 141

  Fly   568 RPYLCLVCGKRFLTGSVFYQHRLIHRGERRYECEECGKRFYRADALKNHQRIHTGEKPYSCLFCT 632
                   |||.|...|...:|..||.|.|.:.|..|.:||..|..|.:|.|||:||:||.|..|.
  Rat   142 -------CGKTFKRSSHLRRHCNIHAGLRPFRCVLCPRRFREAGELAHHHRIHSGERPYQCPSCR 199

  Fly   633 KTFRQRGDRDKHIRARHSHL------------------DANSRLMMQ--MQKFQLE--------- 668
            ..|.:.....:|.:.:|..|                  |.:..:.:|  :|:...|         
  Rat   200 VRFTEANTLRRHYKRKHPELVGMPVRLCPPNPRPQPLWDDDEGVPVQEGVQEESPEGKEPAWPIS 264

  Fly   669 --------TAAAQKAQSHNPEQQDNDVAGGASTSDVPSGSGFMSTEP 707
                    ||.......|..|.||..|:||     :|:..|.....|
  Rat   265 STSPLSGCTAGGSAGAGHGQEGQDTLVSGG-----IPAVEGDQKQGP 306

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
topiNP_649945.1 C2H2 Zn finger 230..250 CDD:275368
C2H2 Zn finger 277..297 CDD:275368
C2H2 Zn finger 431..453 CDD:275368
COG5048 <450..647 CDD:227381 41/143 (29%)
C2H2 Zn finger 469..490 CDD:275368
zf-C2H2 511..533 CDD:278523 5/21 (24%)
C2H2 Zn finger 513..564 CDD:275368 10/50 (20%)
C2H2 Zn finger 541..561 CDD:275368 1/19 (5%)
zf-H2C2_2 555..581 CDD:290200 4/25 (16%)
C2H2 Zn finger 572..592 CDD:275368 6/19 (32%)
zf-H2C2_2 585..609 CDD:290200 9/23 (39%)
zf-C2H2 598..620 CDD:278523 8/21 (38%)
C2H2 Zn finger 600..620 CDD:275368 8/19 (42%)
zf-H2C2_2 612..637 CDD:290200 12/24 (50%)
C2H2 Zn finger 628..646 CDD:275368 4/17 (24%)
Zfp524NP_001102375.1 COG5048 <102..218 CDD:227381 41/146 (28%)
C2H2 Zn finger 111..131 CDD:275368 5/19 (26%)
zf-H2C2_2 123..148 CDD:290200 11/55 (20%)
C2H2 Zn finger 139..159 CDD:275368 7/50 (14%)
zf-H2C2_2 151..174 CDD:290200 7/22 (32%)
C2H2 Zn finger 167..187 CDD:275368 8/19 (42%)
zf-H2C2_2 179..203 CDD:290200 11/23 (48%)
C2H2 Zn finger 195..216 CDD:275368 4/20 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24390
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.010

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