DRSC/TRiP Functional Genomics Resources

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Protein Alignment topi and AgaP_AGAP012007

DIOPT Version :9

Sequence 1:NP_649945.1 Gene:topi / 41199 FlyBaseID:FBgn0037751 Length:814 Species:Drosophila melanogaster
Sequence 2:XP_320526.4 Gene:AgaP_AGAP012007 / 1280665 VectorBaseID:AGAP012007 Length:257 Species:Anopheles gambiae


Alignment Length:263 Identity:65/263 - (24%)
Similarity:99/263 - (37%) Gaps:62/263 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   486 SEEKHLNKKKREKETRNTGAGRIRQYLCDICGKSYTQSSHLWQHLRFHQGVKPFVCQEENCDRKF 550
            |.|.|.|..:.:.:....      :|:||:|.|....||||..|.:.|...||:.| ...|:|.|
Mosquito     8 SLEWHRNYHRSKNQPPKV------RYICDVCRKECNSSSHLHLHRKIHLEHKPYPC-TYGCNRSF 65

  Fly   551 TIRPDLNDHIRKCHTGERPYLCLVCGKRFLTGSVFYQHRLIHRGE-------------------- 595
            :...:...|:.:.||.|:.:.|..||:.|:.....:.||.....|                    
Mosquito    66 SSSGNRQKHVARMHTHEKKFHCAQCGESFIYARQLHTHRERKHAEHTKNTNGLFRCARCKDTFDT 130

  Fly   596 ----------------RRYECEECGKRFYRADALKNHQRIHT-GEKPYSCLFCTKTFRQRGDRDK 643
                            |.:||..|.|||.::..|:||...|| |.:.:.|..|:|.|...||...
Mosquito   131 EDAFRQHLKTSGCLELRAFECVLCAKRFKQSTHLRNHLLTHTNGVRAHGCEHCSKRFTLLGDLKV 195

  Fly   644 HIRARHSHL-DANSRLMMQMQKFQLETAAAQKAQSHNPEQQDNDVAGGASTSDVPSGSGFMSTEP 707
            |   |.:|. :...|.....||.....|..::..:|:|...              |||..:|:..
Mosquito   196 H---RRTHTKEKPFRWTKITQKKPASLANVKEKHTHSPHHM--------------SGSKRLSSAE 243

  Fly   708 SVA 710
            .:|
Mosquito   244 VIA 246

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
topiNP_649945.1 C2H2 Zn finger 230..250 CDD:275368
C2H2 Zn finger 277..297 CDD:275368
C2H2 Zn finger 431..453 CDD:275368
COG5048 <450..647 CDD:227381 52/197 (26%)
C2H2 Zn finger 469..490 CDD:275368 2/3 (67%)
zf-C2H2 511..533 CDD:278523 10/21 (48%)
C2H2 Zn finger 513..564 CDD:275368 17/50 (34%)
C2H2 Zn finger 541..561 CDD:275368 5/19 (26%)
zf-H2C2_2 555..581 CDD:290200 8/25 (32%)
C2H2 Zn finger 572..592 CDD:275368 6/19 (32%)
zf-H2C2_2 585..609 CDD:290200 10/59 (17%)
zf-C2H2 598..620 CDD:278523 9/21 (43%)
C2H2 Zn finger 600..620 CDD:275368 8/19 (42%)
zf-H2C2_2 612..637 CDD:290200 10/25 (40%)
C2H2 Zn finger 628..646 CDD:275368 7/17 (41%)
AgaP_AGAP012007XP_320526.4 C2H2 Zn finger 29..49 CDD:275368 9/19 (47%)
C2H2 Zn finger 57..79 CDD:275368 5/22 (23%)
C2H2 Zn finger 87..104 CDD:275368 4/16 (25%)
C2H2 Zn finger 121..140 CDD:275368 0/18 (0%)
C2H2 Zn finger 151..171 CDD:275368 8/19 (42%)
C2H2 Zn finger 180..200 CDD:275368 8/22 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24390
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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