Protein Alignment topi and LOC116411620

DIOPT Version :9

• Sequence 1: NP_649945.1
• Gene: topi / 41199
• FlyBaseID: FBgn0037751
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: XP_031760140.1
• Gene: LOC116411620 / 116411620
• -ID: -
• Length: 428
• Species: Xenopus tropicalis
• Alignment Length: 498
• Identity: 133/498 - (26%)
• Similarity: 191/498 - (38%)
• Gaps: 126/498 - (25%)

  Fly   157 EAKPIEVAVPQQEKP----HLVP--TVSAPPAPLSKPASERVIRENQVRLRRYIKDEM-KYDLAT 214
            ||..:.:.| ::|.|    |:.|  :.:|||.....|.:|.:    |::     |:|. ..|..|
 Frog     8 EAGMLVIKV-KEEAPDCADHVTPMGSSAAPPTDGGSPEAEML----QIK-----KEEPDPEDHQT 62

  Fly   215 GIESSRKNAAKGPNECTMCDRKFVHASGLVRHMEKHALDLIPSQTSEQPHTIPAAGLHVVVKCNS 279
            .:|||......|.||       .:.:||    .:|...::.||.:|:...||....     .|.:
 Frog    63 PMESSAAPLTDGDNE-------KLQSSG----AQKLQTNMEPSTSSDNCATISPPS-----DCAN 111

  Fly   280 CGRIFYDPQVAFRHGLIHDSEHSTMRQSPMTQVPSNRADFNELLLDGEMLIDNDPAFATSNQNTN 344
            ||                  :.|.:.....||                      |...|.:|...
 Frog   112 CG------------------QSSDLLAHTCTQ----------------------PGNVTDSQTRR 136

  Fly   345 PPKKEMFSSLILGSVLQCEFCEYIFADIAELLVHSASHVAERRFECTACDIQMNTAKEASIHFQT 409
            .|||:.||         |..|...|.....|..|...|:..:.|.||.|............|..|
 Frog   137 EPKKKGFS---------CSECGKCFKYRKYLHQHQMVHLKLKPFPCTECGKGFRFKSSLHKHQMT 192

  Fly   410 DCIFMREAIRSLNVTLSRYFVCNVCELKFA-NTDLLQEHRCTSFHYFPRLNENGKKLLLPCDFCD 473
            .             |..:.|.|..|....: .:||...|          |...|:| ...|..|.
 Frog   193 H-------------TGEKPFTCTECGKGLSYRSDLWSHH----------LVHTGEK-PFTCTECG 233

  Fly   474 VNFEFAHDFLAHSEEKHLNKKKREKETRNTGAGRIRQYLCDICGKSYTQSSHLWQHLRFHQGVKP 538
            ..|         ..:.||    :..|..:||.   :.:.|..|||.:..:|.|.||...|.||||
 Frog   234 KAF---------GNKLHL----KRHEMIHTGE---KPFTCTECGKGFQNNSILQQHRMVHAGVKP 282

  Fly   539 FVCQEENCDRKFTIRPDLNDHIRKCHTGERPYLCLVCGKRFLTGSVFYQHRLIHRGERRYECEEC 603
            |.|:|  |.:.|:.:|:|..| :..||..:|:.|..||:.|...|...:||::|.||:.:.|.||
 Frog   283 FTCRE--CGKGFSNKPNLQKH-QMIHTELKPFTCTECGRGFSFKSSLQRHRMVHTGEKPFTCTEC 344

  Fly   604 GKRFYRADALKNHQRIHTGEKPYSCLFCTKTFRQRGDRDKHIR 646
            ||.|.....|::||:|||||||::|..|.|.|..||...:|.|
 Frog   345 GKGFRNKPRLQSHQKIHTGEKPFTCTECGKGFASRGSLMRHHR 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
topi	NP_649945.1	C2H2 Zn finger	230..250	CDD:275368	2/19 (11%)
		C2H2 Zn finger	277..297	CDD:275368	3/19 (16%)
		C2H2 Zn finger	431..453	CDD:275368	5/22 (23%)
		COG5048	<450..647	CDD:227381	69/197 (35%)
		C2H2 Zn finger	469..490	CDD:275368	3/20 (15%)
		zf-C2H2	511..533	CDD:278523	8/21 (38%)
		C2H2 Zn finger	513..564	CDD:275368	21/50 (42%)
		C2H2 Zn finger	541..561	CDD:275368	7/19 (37%)
		zf-H2C2_2	555..581	CDD:290200	9/25 (36%)
		C2H2 Zn finger	572..592	CDD:275368	7/19 (37%)
		zf-H2C2_2	585..609	CDD:290200	11/23 (48%)
		zf-C2H2	598..620	CDD:278523	9/21 (43%)
		C2H2 Zn finger	600..620	CDD:275368	9/19 (47%)
		zf-H2C2_2	612..637	CDD:290200	14/24 (58%)
		C2H2 Zn finger	628..646	CDD:275368	7/17 (41%)
LOC116411620	XP_031760140.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910