Protein Alignment topi and LOC103910897

DIOPT Version :10

• Sequence 1: NP_649945.1
• Gene: topi / 41199
• FlyBaseID: FBgn0037751
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: XP_068076588.1
• Gene: LOC103910897 / 103910897
• -ID: -
• Length: 429
• Species: Danio rerio
• Alignment Length: 463
• Identity: 132/463 - (28%)
• Similarity: 184/463 - (39%)
• Gaps: 102/463 - (22%)

  Fly   203 YIKDEMKYDLATGIESSRKNAAKGPNECTMCDRKFVHASGLVRHMEKHALDLIPSQTSEQPHTIP 267
            ::|.|.|..|.|  :...|...|....||.||:.....|.|..||..|        |.|:|.|
Zfish    43 HVKIEDKTHLET--DCVLKVRDKSCFTCTPCDKSLASKSKLKTHMRIH--------TGEKPFT-- 95

  Fly   268 AAGLHVVVKCNSCGRIFYDPQVAFRHGLIHDSEHSTMRQSPMTQVPSNRADFNELLLDGEMLIDN 332
                     |..||:.|......:||..||..|      .|.|.....:: ||.
Zfish    96 ---------CTQCGKSFSKSSSLYRHMKIHTGE------KPFTCTHCGKS-FNH----------- 133

  Fly   333 DPAFATSNQNTNPPKKEMFSSLILGSVLQCEFCEYIFADIAELLVHSASHVAERRFECTACDIQM 397
             .:|...:...:..:|.          |.|..|...|:..:.|..|...|..|:.|.||.|....
Zfish   134 -SSFLNLHMRIHTGEKP----------LTCPQCGKSFSKSSSLYRHMKIHTGEKPFTCTQCGKSF 187

  Fly   398 NTAKEASIHFQTDCIFMREAIRSLNVTLSRYFVCNVCELKFANTDLLQEH-------------RC 449
            |.:...:.|.:..             |..:.|.|..|...|:::..|.:|             :|
Zfish   188 NCSSSLNKHMRIH-------------TGEKPFTCTQCGKSFSHSSSLNQHMRIHTGEKPFTCPQC 239

  Fly   450 -TSFHYFPRLNEN-----GKKLLLPCDFCDVNFEFAHDFLAHSEEKHLNKKKREKETRNTGAGRI 508
             .||.....||::     |:| ...|..|..:|.     .:.|..||:.....||
Zfish   240 GKSFINSSHLNQHIMIHTGEK-PFTCTQCGKSFN-----CSSSLNKHMRIHTGEK---------- 288

  Fly   509 RQYLCDICGKSYTQSSHLWQHLRFHQGVKPFVCQEENCDRKFTIRPDLNDHIRKCHTGERPYLCL 573
             .:.|..||||::|||.|.||:..|.|.|||.|.:  |.:.|:....|.:|: |.||..:.|:||
Zfish   289 -PFTCTQCGKSFSQSSSLNQHIMIHTGKKPFTCTQ--CGKSFSQSSYLKNHM-KIHTSVKEYVCL 349

  Fly   574 VCGKRFLTGSVFYQHRLIHRGERRYECEECGKRFYRADALKNHQRIHTGEKPYSCLFCTKTFRQR 638
            .|.|.|:|.:...:|:.||.||:.|:|..|.|||.:...||.|:|||||:|||.|..|:|.|...
Zfish   350 ECEKTFITAAELKRHQRIHTGEKPYKCSHCSKRFTQLGTLKTHERIHTGDKPYKCSHCSKRFTHT 414

  Fly   639 GDRDKHIR 646
            |...||.|
Zfish   415 GTLKKHQR 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
topi	NP_649945.1	C2H2 Zn finger	230..250	CDD:275370	8/19 (42%)
		C2H2 Zn finger	277..297	CDD:275370	6/19 (32%)
		C2H2 Zn finger	431..453	CDD:275368	7/35 (20%)
		COG5048	<450..647	CDD:227381	75/202 (37%)
		C2H2 Zn finger	469..490	CDD:275368	4/20 (20%)
		C2H2 Zn finger	513..564	CDD:275368	22/50 (44%)
		C2H2 Zn finger	541..561	CDD:275368	5/19 (26%)
		C2H2 Zn finger	572..592	CDD:275368	7/19 (37%)
		C2H2 Zn finger	600..620	CDD:275368	9/19 (47%)
		zf-H2C2_2	612..637	CDD:463886	15/24 (63%)
		C2H2 Zn finger	628..646	CDD:275368	7/17 (41%)
LOC103910897	XP_068076588.1	C2H2 Zn finger	68..88	CDD:275368	8/19 (42%)
		zf-H2C2_2	81..105	CDD:463886	12/42 (29%)
		C2H2 Zn finger	96..116	CDD:275368	6/19 (32%)
		zf-H2C2_2	108..133	CDD:463886	8/31 (26%)
		C2H2 Zn finger	124..144	CDD:275368	3/32 (9%)
		COG5048	127..>428	CDD:227381	101/352 (29%)
		C2H2 Zn finger	152..172	CDD:275368	5/19 (26%)
		C2H2 Zn finger	180..200	CDD:275368	5/19 (26%)
		C2H2 Zn finger	208..228	CDD:275368	5/19 (26%)
		C2H2 Zn finger	236..256	CDD:275368	5/19 (26%)
		C2H2 Zn finger	264..284	CDD:275368	6/24 (25%)
		C2H2 Zn finger	292..312	CDD:275368	11/19 (58%)
		C2H2 Zn finger	320..340	CDD:275368	6/22 (27%)
		C2H2 Zn finger	348..368	CDD:275368	7/19 (37%)
		C2H2 Zn finger	376..396	CDD:275368	9/19 (47%)
		C2H2 Zn finger	404..424	CDD:275368	8/19 (42%)