DRSC/TRiP Functional Genomics Resources

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Protein Alignment topi and si:dkeyp-121d2.7

DIOPT Version :9

Sequence 1:NP_649945.1 Gene:topi / 41199 FlyBaseID:FBgn0037751 Length:814 Species:Drosophila melanogaster
Sequence 2:XP_003200019.1 Gene:si:dkeyp-121d2.7 / 100536535 ZFINID:ZDB-GENE-141215-52 Length:463 Species:Danio rerio


Alignment Length:239 Identity:76/239 - (31%)
Similarity:108/239 - (45%) Gaps:30/239 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   462 GKKLLLPCDFCDVNF---------EFAHDFLAHSE---EKHLNKKKREKET-RNTGA-GRIRQYL 512
            |...|.||....|.|         :.|....:||.   |..|......||. ..:|| .....:.
Zfish   228 GSPSLEPCGSEGVGFIGLDGLCSSQQAMSSSSHSRDPAELQLPSAPATKEEGEESGAESADMMHF 292

  Fly   513 CDICGKSYTQSSHLWQHLRFHQGVKPFVCQEENCDRKFTIRPDLNDHIRKC-HTGERPYLCLVCG 576
            |..||..:|.||.|.:|.......:|:.|..  |.|.|.....|..|  :| .||::|:.|.:||
Zfish   293 CVRCGSGFTSSSDLIKHSCPAAEERPYQCSA--CGRAFGHAWSLKSH--ECVQTGDQPHHCELCG 353

  Fly   577 KRFLTGSVFYQHRLIHRGERRYECEECGKRFYRADALKNHQRIHTGEKPYSCLFCTKTFRQRGDR 641
            |||.......:|:|:|.|||.:.|.:||:.|.|...|:.||||||||:||.|..|.|.|    .|
Zfish   354 KRFTHSRSLERHQLVHTGERPHRCPQCGRSFSRLGNLERHQRIHTGERPYECEACGKRF----SR 414

  Fly   642 DKHIRARHSHLDANSRLMMQMQKFQLETA--AAQKAQSHNPEQQ 683
            .:::: ||.|:.....::    |..|:..  .||..|:.:..:|
Zfish   415 VEYLK-RHQHIHIGDAML----KHTLQNTQHCAQCNQTFSDSEQ 453

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
topiNP_649945.1 C2H2 Zn finger 230..250 CDD:275368
C2H2 Zn finger 277..297 CDD:275368
C2H2 Zn finger 431..453 CDD:275368
COG5048 <450..647 CDD:227381 67/199 (34%)
C2H2 Zn finger 469..490 CDD:275368 7/32 (22%)
zf-C2H2 511..533 CDD:278523 8/21 (38%)
C2H2 Zn finger 513..564 CDD:275368 16/51 (31%)
C2H2 Zn finger 541..561 CDD:275368 6/19 (32%)
zf-H2C2_2 555..581 CDD:290200 12/26 (46%)
C2H2 Zn finger 572..592 CDD:275368 8/19 (42%)
zf-H2C2_2 585..609 CDD:290200 10/23 (43%)
zf-C2H2 598..620 CDD:278523 9/21 (43%)
C2H2 Zn finger 600..620 CDD:275368 9/19 (47%)
zf-H2C2_2 612..637 CDD:290200 15/24 (63%)
C2H2 Zn finger 628..646 CDD:275368 5/17 (29%)
si:dkeyp-121d2.7XP_003200019.1 C2H2 Zn finger 293..313 CDD:275370 8/19 (42%)
C2H2 Zn finger 321..341 CDD:275368 7/23 (30%)
zf-C2H2 347..369 CDD:278523 8/21 (38%)
C2H2 Zn finger 349..369 CDD:275368 8/19 (42%)
zf-H2C2_2 361..386 CDD:290200 10/24 (42%)
COG5048 373..>451 CDD:227381 30/86 (35%)
C2H2 Zn finger 377..397 CDD:275368 9/19 (47%)
zf-H2C2_2 389..414 CDD:290200 15/28 (54%)
C2H2 Zn finger 405..425 CDD:275368 8/24 (33%)
C2H2 Zn finger 441..458 CDD:275368 4/13 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24390
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.100

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