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Protein Alignment topi and zxdc

DIOPT Version :9

Sequence 1:	NP_649945.1	Gene:	topi / 41199	FlyBaseID:	FBgn0037751	Length:	814	Species:	Drosophila melanogaster
Sequence 2:	XP_031757030.1	Gene:	zxdc / 100495694	XenbaseID:	XB-GENE-1033000	Length:	869	Species:	Xenopus tropicalis

Alignment Length:	611	Identity:	128/611 - (20%)
Similarity:	211/611 - (34%)	Gaps:	191/611 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   249 KHALDLIPSQTSEQPHTIPAA----GLHVVVKCNSCGRIFYDPQVAFRHGLIHDSEHSTMRQSPM 309
            |.:||..|.:..:||..:..|    .:::|:..:.....   |.|.        .||..:|.||.
Frog    25 KESLDESPDEEEKQPGLVNEAEDGPPVYMVLNLSEEAAA---PAVT--------GEHDLVRPSPS 78

  Fly   310 TQVPSNRADFNELLLDGEML-----------------------IDNDPAFATSNQNTNP------ 345
            :........:..:.|:..:|                       |...||:|:..:..:.
Frog    79 SSSELGLPGYVTVRLENGVLTLGGRGSESVEPAEPPVSNQVSDIQAQPAWASELEAASSSGAAQR 143

  Fly   346 -PK-------------KEMFSSLILGSV--LQCEF---------------------CEYIFADIA 373
             |:             .|..:..::|.:  ||...                     |...|....
Frog   144 FPEDLEDVDLVLRDSMDEQVAGFLVGEIGELQVNLGEALDLARKGVLLVFRCPEPGCAKAFDRKQ 208

  Fly   374 ELLVHSASHV-AERRFECTA--CDIQMNTAKEASIHFQTDCIFMREAIRSLNVTLSRYFVCNV-- 433
            :|.||..||. .:|.|:||.  |.....|..:...|.|:.             ...|.|.|:|
Frog   209 QLKVHLLSHTEGQRPFKCTVANCGWSFTTLYKLKRHLQSH-------------DKQRPFSCDVPG 260

  Fly   434 CELKFANTDLLQEHRCTSFHYFPRLNENGKKLLLPCDFCDVNFEFAHDFLAHSEEKHLNKKKREK 498
            |...|.....|:.|          |..:.::.|..||.|..:|..|.....| ...|...:
Frog   261 CGKSFTTVYNLKAH----------LKAHEQENLFRCDTCGESFPTATKLSGH-RRMHFEPE---- 310

  Fly   499 ETRNTGAGRIRQYLCDI--CGKSYTQSSHLWQHLRFH-QGVKPFVCQEENCDRKFTIRPDLNDHI 560
                      |.|.|:.  |.|::...:.|:.|.|.| :..:.|:|....|::::.....|..|:
Frog   311 ----------RPYKCEFPGCDKTFITVTALFSHHRAHVREQEQFICSFPGCNKQYDKACRLKIHL 365

  Fly   561 RKCHTGERPYLCLV--CGKRFLTGSVFYQHRLIHRGERRYEC--EECGKRFYRADALKNHQRIHT 621
            |. ||||||::|..  ||..|.:.|...:|:..|..:|||.|  |.|||.|.||:.||.|...|.
Frog   366 RS-HTGERPFICDFDGCGWSFTSMSKLLRHKRKHEDDRRYPCPVEGCGKSFTRAEHLKGHSITHL 429

  Fly   622 GEKPYSCLF--CTKTFRQRGDRDKHIRARHSHLDANSRLMMQMQKFQLETAAAQKAQSHNPEQQD 684
            |.||:.|..  |...|..|           |.|..:|:..:|
Frog   430 GTKPFECPIDGCGAKFSAR-----------SSLYIHSKKHLQ----------------------- 460

  Fly   685 NDVAGGASTSDVPSGSGFMSTEPSVAE---MQYSITPEQQEEMVCVPIDEVNNSFFMSHYMQAVP 746
             ||....:...|||.:...:::.|:..   .|::.:|:...::      |.::|...|..:.::
Frog   461 -DVETSKTRCLVPSCNKMFTSKQSMKSHMVKQHNFSPDLLTQL------EASSSLTPSSELTSL- 517

  Fly   747 MEEDGSGQHIIVFEQPGQNMDMMSIY 772
                  ||:.:      .|:|:.|::
Frog   518 ------GQNDL------SNLDLSSLF 531

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.