Protein Alignment Whamy and WAS

DIOPT Version :9

• Sequence 1: NP_001036699.1
• Gene: Whamy / 41198
• FlyBaseID: FBgn0037750
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: XP_016885275.1
• Gene: WAS / 7454
• HGNCID: 12731
• Length: 590
• Species: Homo sapiens
• Alignment Length: 476
• Identity: 118/476 - (24%)
• Similarity: 153/476 - (32%)
• Gaps: 198/476 - (41%)

  Fly   127 PPPAVRP------PPHYADNVSINASLDGMKSSSSSNSLDRYLGAPPSVALAGPSFATSVLVSSK 185
            ||..:.|      ||  ...:|:..:...:::...::|  ||.|.|    ..|||.|.......|
Human   175 PPLPLHPGGDQGGPP--VGPLSLGLATVDIQNPDITSS--RYRGLP----APGPSPADKKRSGKK 231

  Fly   186 G-SKYEISGPVNFQHVSGDVTRDRTRNAFDL-NADPNDKVLRKYMMERGITEADISDMRRQEVIK 248
            . ||.:|..|..|:||| .|..| .:|.||: |.||:   ||......||:||.::|....::|
Human   232 KISKADIGAPSGFKHVS-HVGWD-PQNGFDVNNLDPD---LRSLFSRAGISEAQLTDAETSKLI- 290

  Fly   249 KIIHSNFTWMPPKSDLQAQPKVQDHARPLLYATISTNNQITPPPSPPPPPIATISRPTEAPNFSN 313
                  :.::..:..|:|..:......||                |||||      |:...|
Human   291 ------YDFIEDQGGLEAVRQEMRRQEPL----------------PPPPP------PSRGGN--- 324

  Fly   314 YASLTSRFVDISDMDLPAPTPAAPTPFQPAEVGSVIPVQVQPQQSVKPKVPPPPSAVMAKNTHGY 378
                          .||.|      |......|...|            :||.|.
Human   325 --------------QLPRP------PIVGGNKGRSGP------------LPPVPL---------- 347

  Fly   379 PAAIDIRQVRPSVAPKVANETYATISPQRKVGSMRVPPPAPPKPTIVPHTNSTISNGSLYAVSPV 443
                       .:||                     |||.|..|
Human   348 -----------GIAP---------------------PPPTPRGP--------------------- 359

  Fly   444 QYAPVAKPAPPAAPAKPTSRSSAVYMTPLSAQKTQISSTPVPVSPPPPTAASVGVPPPPPAPPAG 508
              .|..:..||                                 ||||.|.....|.|||.|.||
Human   360 --PPPGRGGPP---------------------------------PPPPPATGRSGPLPPPPPGAG 389

  Fly   509 VPPAPPPMPVFGAGGAPPPPPPPSSGMAGVPPPPPMQKSQPKAVSAASTG-GDPRDAFLESIRQG 572
            .||.|||        .||||||||||....|||.|     |..|.|.... |..|.|.|:.||||
Human   390 GPPMPPP--------PPPPPPPPSSGNGPAPPPLP-----PALVPAGGLAPGGGRGALLDQIRQG 441

  Fly   573 VKLKKVDQKAATISGIKPRPE 593
            ::|.|. ..|...|.::|.|:
Human   442 IQLNKT-PGAPESSALQPPPQ 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Whamy	NP_001036699.1	WH2	558..>580	CDD:280384	10/22 (45%)
WAS	XP_016885275.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001481
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.860