Protein Alignment Whamy and Wasl

DIOPT Version :9

• Sequence 1: NP_001036699.1
• Gene: Whamy / 41198
• FlyBaseID: FBgn0037750
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_082735.2
• Gene: Wasl / 73178
• MGIID: 1920428
• Length: 501
• Species: Mus musculus
• Alignment Length: 555
• Identity: 141/555 - (25%)
• Similarity: 181/555 - (32%)
• Gaps: 237/555 - (42%)

  Fly   109 FFSFQPPSMQVSSDVFAHPPPAVRPPPHYADNVSINASLDGMKSSSSSNSLDRYLGAP--PSVAL 171
            |.:|...:.||:.: ||:...|.:......|       |.|.:...|....|    ||  |::.:
Mouse   104 FHTFAGDTCQVALN-FANEEEAKKFRKAVTD-------LLGRRQRKSEKRRD----APNGPNLPM 156

  Fly   172 A-----GPSFATSVLVSS------------KG-------SKYEISGPVNFQHVSGDVTRDRTRNA 212
            |     .|...|:....|            ||       :|.:|..|.||||: |.|..| ....
Mouse   157 ATVDIKNPEITTNRFYGSQVNNISHTKEKKKGKAKKKRLTKADIGTPSNFQHI-GHVGWD-PNTG 219

  Fly   213 FDL-NADPNDKVLRKYMMERGITEADISDMRRQEVIKKIIHSNFTWMPPKSDLQAQPKVQDHARP 276
            ||| |.||.   |:......||:||.:.|....:||...|.........|::|:.|      |.|
Mouse   220 FDLNNLDPE---LKNLFDMCGISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQ------APP 275

  Fly   277 LLYATISTNNQITPPPS---PPPPPIATISRPTEAPNFSNYASLTSRFVDISDMDLPAPTPAAPT 338
                        .||||   |||||                               |.|..:.|.
Mouse   276 ------------PPPPSRGGPPPPP-------------------------------PPPHSSGPP 297

  Fly   339 PFQPAEVGSVIPVQVQPQQSVKPKVPPPPSAVMAKNTHGYPAAIDIRQVRPSVAPKVANETYATI 403
            |  |...|...|             |||||..                  |:.||
Mouse   298 P--PPARGRGAP-------------PPPPSRA------------------PTAAP---------- 319

  Fly   404 SPQRKVGSMRVPPPAPPKPTIVPHTNSTISNGSLYAVSPVQYAPVAKPAPPAAPAKPTSRSSAVY 468
                       |||.|.:|.:|              |.|   .|..:..||..||.|:|..|.
Mouse   320 -----------PPPPPSRPGVV--------------VPP---PPPNRMYPPPPPALPSSAPSG-- 354

  Fly   469 MTPLSAQKTQISSTPVPVSPPPPTAASVGVPPPPPAPPAGVPPAPPPMPVFGAGGAPPPPPPPSS 533
                            |..||||:.|....|||||      ||.|||       |.||||..||.
Mouse   355 ----------------PPPPPPPSMAGSTAPPPPP------PPPPPP-------GPPPPPGLPSD 390

  Fly   534 GMAGVPPPPPMQKSQPKAVSAASTGGDPRDAFLESIRQGVKLKKVDQKAATISGIKPRPERKPVT 598
            |...||.|     |..||            |.|:.||:|.:||||:|.:            :||:
Mouse   391 GDHQVPAP-----SGNKA------------ALLDQIREGAQLKKVEQNS------------RPVS 426

  Fly   599 TD----FLSELKLGITLRRVKN------PADNPYS 623
            ..    .|.:::.||.|:.|.:      |...|.|
Mouse   427 CSGRDALLDQIRQGIQLKSVSDGQESTPPTPAPTS 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Whamy	NP_001036699.1	WH2	558..>580	CDD:280384	9/21 (43%)
Wasl	NP_082735.2	WH1	28..135	CDD:395450	8/38 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	135..159		7/27 (26%)
		PBD	199..256	CDD:395634	23/61 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	263..403		73/295 (25%)
		WH2_N-WASP_r1	398..424	CDD:409217	14/54 (26%)
		WH2_hN-WASP_r2_like	425..449	CDD:409218	6/23 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	442..501		5/20 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001481
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	4	3.860