Protein Alignment Whamy and waslb

DIOPT Version :10

• Sequence 1: NP_001036699.1
• Gene: Whamy / 41198
• FlyBaseID: FBgn0037750
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_957353.2
• Gene: waslb / 394034
• ZFINID: ZDB-GENE-040426-718
• Length: 518
• Species: Danio rerio
• Alignment Length: 657
• Identity: 155/657 - (23%)
• Similarity: 214/657 - (32%)
• Gaps: 282/657 - (42%)

  Fly    37 DEMLQLYLRKANLSDDLERLPAIVRRAYVYD--------------IIRSNKEPGYWV-VISCSIS 86
            :|:|..:|.|..:|     |.:.|.:.|..|              :::.|.:..|:: ||.....
Zfish    24 NEVLFNHLGKKCIS-----LSSAVVQVYAADRNSSWVKKCCGVACLVKDNTQRSYYIRVIDMKDG 83

  Fly    87 SCQLHQPKVSLMLSTVVLNAA--VFFSFQPPSMQVSSDVFAHPPPAVRPPPHYADNVSINASLDG 149
            .....|.    |.:...:|.:  .|.:|...:.|:..: ||:...|.|       ..|....|.|
Zfish    84 KTLFEQE----MYNNFSINCSRPYFITFSGDNCQIGLN-FANEEEAKR-------FRSAIGELVG 136

  Fly   150 MKSSSSSNSLDRYLGAPPSVALAGPS-----FATSVLVS-------------------------- 183
            .||..:....:...|  |||: :|||     .||..:.:
Zfish   137 RKSRRTEKRREPPNG--PSVS-SGPSGPALPMATVDIKNPEITNQRYHNNTQMNNLQSNFNRAKD 198

  Fly   184 -SKG---------SKYEISGPVNFQHVSGDVTRDRTRNAFDL-NADPNDKVLRKYMMERGITEAD 237
             |||         ||.||..|.||:|| |.|..| ....||| |.||:   |:|.....||:|.:
Zfish   199 KSKGKNNNKKKKISKAEIGTPSNFRHV-GHVGWD-PNTGFDLNNLDPD---LKKLFDMCGISEDE 258

  Fly   238 ISDMRRQEVIKKIIHSNFTWMPPKSDLQAQPKVQDHARPLLYATISTNNQITPPPSPP-----PP 297
            :.|....:||..:|.........|::::.|                     .|||.||     ||
Zfish   259 LKDKETSKVIYDLIEKQGGVEAVKNEMRRQ---------------------APPPPPPSRGGAPP 302

  Fly   298 PIATISRPTEAPNFSNYASLTSRFVDISDMDLPAPTPAAPTPFQPAEVGSVIPVQVQPQQSVKPK 362
            |                               |.|..:||
Zfish   303 P-------------------------------PPPHNSAP------------------------- 311

  Fly   363 VPPPPSAVMAKNTHGYPAAIDIRQVRPSVAPKVANETYATISPQRKVGSMRVPPPAPPKPTIVPH 427
             ||||                                     |.|..|:   |||.||
Zfish   312 -PPPP-------------------------------------PSRGRGA---PPPPPP------- 328

  Fly   428 TNSTISNGSLYAVSPVQYAPVAKPAPPAAPAKPTSRSSAVYMTPLSAQKTQISSTPVPVSPPPPT 492
                            ..||.:.| ||..|::|                    ....|..||||:
Zfish   329 ----------------SRAPTSAP-PPPPPSRP--------------------GMGAPPPPPPPS 356

  Fly   493 AASVGVPPPPPAPPAG--VPPAPPPMPVFGAGGAPPPPPPPSSGMAGVPPPPPMQKSQPKAVSAA 555
            ......|||||.|.:.  .|||||.:     ||||||||||       ||||......|......
Zfish   357 RGPTQAPPPPPPPHSASISPPAPPSI-----GGAPPPPPPP-------PPPPGPPPPGPPPAQDV 409

  Fly   556 STGGDP--RDAFLESIRQGVKLKKVDQKAATISGIKPRPERKPVTTD----FLSELKLGITLRRV 614
            .:|..|  |.|||:.||:|.:||||||.           .:.||:|.    .|.:::.||.|:.|
Zfish   410 DSGDSPGGRSAFLDQIREGAQLKKVDQN-----------NKPPVSTGGRGALLDQIRQGIQLKTV 463

  Fly   615 KNPADNP 621
            .:..::|
Zfish   464 TDAPESP 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Whamy	NP_001036699.1	WH2	558..>580	CDD:460490	13/23 (57%)
waslb	NP_957353.2	EVH1_WASP-like	37..131	CDD:269916	20/110 (18%)
		PBD	215..272	CDD:395634	24/61 (39%)
		WH2_N-WASP_r1	416..440	CDD:409217	13/34 (38%)
		actin-binding sequence	431..434	CDD:409217	2/2 (100%)
		WH2_hN-WASP_r2_like	442..466	CDD:409218	7/23 (30%)