DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Whamy and viro-2

DIOPT Version :9

Sequence 1:	NP_001036699.1	Gene:	Whamy / 41198	FlyBaseID:	FBgn0037750	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_741212.2	Gene:	viro-2 / 3565684	WormBaseID:	WBGene00015107	Length:	616	Species:	Caenorhabditis elegans

Alignment Length:	516	Identity:	127/516 - (24%)
Similarity:	204/516 - (39%)	Gaps:	117/516 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 SFATSVLVSSKGSK--YEISGPVNFQHVSG----DVTRD---RTRNAFDLNADPNDKVLRKYMME 230
            ||..::..|...||  .||..|.:|:||.|    ||..|   :.|:..::| :|.::.:.|.::.
Worm   154 SFFHNLFKSHSESKNQVEIGAPTDFRHVDGVKLTDVQEDLYMQVRSKLNVN-NPEEEEIVKQVIV 217

  Fly   231 RGITEADISDMRRQE--VIKKIIHSNFTWMPPKSDL-QAQPKVQDHARPLLYATISTNNQITP-- 290
            |.......|.|.::|  .:|::...|......||.. :.:|||:|.::|::  .:.|.:.:.|
Worm   218 RNEDHIRQSLMVKKESQTVKEVKDKNKDKKKSKSFFGRNKPKVEDVSQPIV--PVITGDPLNPDW 280

  Fly   291 ---PPSPPPPPIATISRPTEAPNFSNYASLTSRFVDISDMDLPAPTPAAPT---------PFQPA 343
               ..|.......:.|..|.|.:|.:..:..:..:..:|.:.|.......|         .|:..
Worm   281 TSNSTSSMSASFRSSSTVTAATSFKHSHTFAADPIKTTDWETPRKDTYGSTNQRQPQNIYKFEQE 345

  Fly   344 EVGSVIPVQVQPQQSVKPKVPP-----PPSAVMAK---NTHGYPAAIDIRQ--VRPSVAPKVANE 398
            .|.....::........|::|.     .|...|.:   :|...|...|..:  .:|...||
Worm   346 HVEQTYQIEKIEMDDTPPELPSRGASRNPEDQMTRGGLSTPRIPTHRDSYRWATKPDTVPK---- 406

  Fly   399 TYATISPQRKVGSMRVPPPAPPKPTIVPHTNSTISNGSLYAVSPVQYAPVAKPAPPAAPAKPTSR 463
                          :.|||.|..|:   |::..........|.|.....||.|.||:||  ||.:
Worm   407 --------------QTPPPTPNAPS---HSHQVDQFAEFKLVEPKTPTRVAPPPPPSAP--PTIK 452

  Fly   464 SSAVYMTPLSAQKTQISSTPVPV---SPPPPTAASVGVPPPPPAP-PAGV---PPAPPPM-PVFG 520
                  .|:|...:..|:||...   :||||:.    :|.|.|:| ||.|   ||.|||: |:..
Worm   453 ------FPISTGPSYSSTTPPTTPKPAPPPPSR----IPNPSPSPQPAEVSKSPPPPPPLPPIAT 507

  Fly   521 AGGAPPPPPPPSSGMAGVPPPPP---MQKSQPKAV--SAASTGGDPRDAFLESIR---QGVKLKK 577
            ....|||||||       |||||   .:.|.|..|  :|.......|.:.::.||   :...|:|
Worm   508 PSSVPPPPPPP-------PPPPPALEQEISGPPTVRLTAVPESNSDRRSLMDQIRSTDRSQVLRK 565

  Fly   578 VDQKAATISGIKPRPERKPVTT---------DFLSELKLGITLRRVKNPADNPYSEESESQ 629
            |.....|...:       |.||         :||...:.||      ||:|:..|::.:.:
Worm   566 VSDTPETRQSV-------PSTTSGTIVDQIQNFLDARRSGI------NPSDSEESDDDDDE 613

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Whamy	NP_001036699.1	WH2	558..>580	CDD:280384	6/24 (25%)
viro-2	NP_741212.2	PH-like	23..133	CDD:388408
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28919
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010